Study Datasets
Bone Histomorphometry
1 uploads
Bone: Femur
Region: Trabecular
Bone Histomorphometry
1 uploads
Bone: Vertebra
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
C1qtnf5 KO Male
M
12wk
B6N(Cg)-C1qtnf5 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
C1qtnf5 KO Female
F
12wk
B6N(Cg)-C1qtnf5 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
C1qtnf5 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
C1qtnf5 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Bone Histomorphometry Bone: Femur Region: Trabecular
| Variable | C1qtnf5 WT Male (Mean ± SD) | C1qtnf5 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Alkaline Phosphatase+ Bone Surface/Bone Surface (AP/BS) (%) | 65.26 ± 2.79 | 34.08 ± 11.64 | <0.001* |
| Alkaline Phosphatase+ Bone Surface/Labeled Bone Surface (AP/L.BS) (%) | 30.21 ± 4.16 | 14.43 ± 7.92 | <0.001* |
| Alkaline Phosphatase+ Bone Surface/Non-Labeled Bone Surface (AP/NL.BS) (%) | 36.76 ± 3.04 | 19.40 ± 5.25 | <0.001* |
| AP+ TRAP+ Labeled Bone Surface/Bone Surface (AP+TRAP+L.BS/BS) (%) | 6.52 ± 1.10 | 1.38 ± 0.69 | <0.001* |
| Body Weight (g) | 25.96 ± 1.60 | 28.68 ± 1.96 | 0.0132* |
| Bone Formation Rate/Bone Surface (BFR/BS) (µm3/µm2/day) | 0.287 ± 0.059 | 0.189 ± 0.074 | 0.0156* |
| Bone Volume/Tissue Volume (BV/TV) (%) | 8.59 ± 1.50 | 9.45 ± 1.72 | 0.3353 |
| Labeled Alkaline Phosphatase+ Surface/Total AP+ Surface (L.S+AP/T.AP) (%) | 44.87 ± 4.16 | 39.66 ± 11.35 | 0.2843 |
| Mineral Apposition Rate (MAR) (µm/day) | 1.25 ± 0.13 | 0.95 ± 0.22 | 0.0068* |
| Mineralizing Surface/Bone Surface (MS/BS) (%) | 22.29 ± 2.38 | 19.03 ± 6.78 | 0.2618 |
| Non-Labeled Alkaline Phosphatase+ Surface/Total AP+ Surface (NL.S+AP/T.AP) (%) | 55.13 ± 4.16 | 60.34 ± 11.35 | 0.2843 |
| Trabecular Number (Tb.N) (#/mm) | 3.81 ± 0.69 | 4.08 ± 0.65 | 0.4708 |
| Trabecular Spacing (Tb.Sp) (µm) | 259.04 ± 56.64 | 230.85 ± 46.23 | 0.3249 |
| Trabecular Thickness (Tb.Th) (µm) | 21.67 ± 1.57 | 23.43 ± 2.65 | 0.1521 |
| TRAP+ Bone Surface/Bone Surface (TRAP/BS) (%) | 32.49 ± 2.50 | 27.71 ± 4.25 | 0.0227* |
| TRAP+ Bone Surface/Labeled Bone Surface (TRAP/L.BS) (%) | 11.01 ± 1.86 | 8.35 ± 3.42 | 0.0921 |
| TRAP+ Bone Surface/Non-Labeled Bone Surface (TRAP/NL.BS) (%) | 21.91 ± 1.75 | 19.55 ± 1.40 | 0.0144* |
| TRAP+ Bone Surface/Total TRAP+ Surface (TRAP/TRAP) (%) | 67.10 ± 5.03 | 66.74 ± 7.20 | 0.9159 |
| TRAP+ Labeled Bone Surface/TRAP+ Bone Surface (TRAP+L.BS/TRAP.BS) (%) | 33.21 ± 3.25 | 28.74 ± 8.47 | 0.2249 |
| TRAP+ Non-Labeled Bone Surface/TRAP+ Bone Surface (TRAP+QS.BS/TRAP.BS) (%) | 66.79 ± 3.25 | 71.26 ± 8.47 | 0.2249 |