Data Submission Portal
Thank you for helping advance research in the skeletal sciences.
Ready to submit your data?
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Before You Begin
A ROSSA account is required to submit data.
What to gather, file formats, and templates before you start.
What types of studies we accept and publication rules.
Step-by-step guides with screenshots are available.
Genetic, drug, gonadectomy, other interventions, and combined study designs.
DEXA, microCT, histomorphometry, mechanical testing, and more, plus microCT and representative images.
Overview of the Submission Process
Follow these steps in order. You can save your progress and return at any time.
After approving the depositor agreement, a unique Study ID (ROSSA...) will be generated. Use this ID in publications to reference your archived data.
- Study Information: Provide Study Summary and Publication Details
- Subject Areas: Specify Research Domains
- Investigators: A Corresponding investigator is required. Mark anyone else as Contributing.
- Set up: Select Relevant Experimental Variables (Genetic, Drug, Gonadectomy, Other Interventions)
- Animal Models: Detail Your Animal Models using the Preconfigured Categories
- Drug Treatments: Add Drug Treatment Plans and Events (if performed)
- Gonadectomy: Add Surgical Procedures (if performed)
- Other Interventions: Add non-drug procedures such as diet, radiation, or exercise (if performed)
- Sample Groups: Define your Sample Groups using the Sample Groups Builder
- Comparison Groups: Detail what Sample Groups will be Compared to Each Other
- Upload Spreadsheet Data: Select Preconfigured Categories to Upload Spreadsheets
- Upload Image Data: Upload microCT Images and Representative Images
Please review each tab within the report to confirm the accuracy of information is consistent with your study outcomes. This report will be publicly shared with the broader research community, so accuracy is essential. Make edits as needed by navigating back to the relevant sections.
- Information
- Data Exploration
- Download Original Data
- Please confirm the information provided is accurate and complete.
- Select "Submit Study" after confirmation or alternatively "Return to Form" to make edits.
- After submission your study will be reviewed by our team and you will be notified of any necessary edits or if your study is approved for publication in the datacenter.
We know it took a team to carry out your study. Use the Share button at the top of any form page to invite colleagues, such as co-investigators, core facility staff, and lab members, to add information and data to your submission.
Team members appear as initials beside the Share button. Invitees need a ROSSA account and are asked to create one with the invited email address if they do not have one. Access can be removed at any time, by you or by the team member. The corresponding investigator reviews and submits the study.
Quick Tips
Follow the order provided
But you may edit existing information at any time. If you go back and edit something, it may impact future sections and will need to be updated.
Save & Continue
By clicking "Save and Continue" at the bottom of every page your work is saved to the database. This button will always look the same, keep an eye out for it!
Pick up on Another Day
If submission is taking longer than expected, no worries you can pick up where you left off on another day. Simply login and go to my submissions and select "Continue Study."
Account & Login
A ROSSA account is required to submit data. If you don't have one, you can create an account here. Already registered? Log in and you'll return to this page automatically.
Submission Scope & Embargo Policy
Submission Scope
Designed for individual skeletal phenotyping studies. For large multi-model screening programs, contact us for custom ingestion support.
Publication & Embargo Policy
Only published studies are publicly displayed. Unpublished data is accepted with an embargo period while you seek publication.
Quick & Detailed Guides
Quick and detailed guides available
We provide both a quick guide and a detailed step-by-step guide with screenshots. The submission form also includes a help module with instructions and tips for each section of the form.
View Full Help GuideExperimental Approaches Currently Accepted
Genetic models
Global knockouts, conditional knockouts, spontaneous and disease models.
Preclinical drug testing
Single agents, cocktails, or sequential treatment regimens.
Gonadectomy
Wild type animals or combined with genetic or drug variables.
Other interventions
Diet and nutrition, radiation, exercise, cell transplantation, circadian disruption, and other non-drug procedures.
Combined studies
Mix genetic, drug, gonadectomy, and other intervention variables in custom animal groupings.
Drug-induced disease models (for example streptozotocin or LPS) are entered under drug treatments.
Phenotyping Analyses Currently Accepted
The upload process accepts your personal spreadsheet data with quantitative measurements generated from individual samples.
Dual X-Ray Absorptiometry
Whole body and regional bone mineral density and content.
Microcomputed Tomography
Trabecular and cortical bone microstructure parameters.
Bone Histomorphometry
Static and dynamic indices of bone formation and resorption.
Mechanical Strength Testing
Three-point bending, compression, and torsional strength measures.
Clinical Chemistry Analytes
Serum and urine biomarkers relevant to skeletal metabolism.
Image Files
You can also upload image files alongside your spreadsheet data.
microCT Images
Raw scan files (Scanco ISQ/AIM or Bruker TIFF) linked to samples, with bone type and region scanned. Publicly downloadable.
Representative Images
Publication-ready figure images, each with a caption that describes it.
Planning For Submission
A little preparation goes a long way. Here's what you can do ahead of time to make your submission as smooth and fast as possible.
Study Information to Gather
You will be asked to provide a study title, a brief summary or abstract, and funding source information during the metadata sections of the submission form. Having these written out ahead of time will save you time.
If your study is published, have the citation or DOI ready. A corresponding investigator is required, so have names and contact details ready for them and for any contributing investigators.
Think about who helped carry out the study, such as co-investigators, core facility staff, and lab members. Once your submission is started, you can invite them to contribute with the Share button. Invitees will need a ROSSA account.
Study Design Details to Gather
Know which animal models were used (strain, genotype, and source) and which experimental variables apply to your study: genetic, drug, gonadectomy, or other interventions.
If animals received drug treatments, gonadectomy, or other interventions such as diet, radiation, or exercise, have the method, timing, and duration ready for each. Include the matching control version of each plan.
Decide how your samples divide into groups and which groups will be compared with each other, for example control versus experimental.
Data Files to Prepare
ROSSA currently accepts spreadsheet data files in CSV format only. For database security purposes we cannot accept Excel file formats (.xlsx, .xls). If your data is in Excel, please convert your files to CSV before submission.
We strongly encourage including a body weight column in your data spreadsheet. Body weight is an important covariate in skeletal phenotyping studies and greatly enhances the interpretability and comparability of your data.
Use consistent units within each column (for example mm or µm, fraction or percent) and make sure header labels match the units in the data.
While ROSSA's data ingestion process is designed to work directly with your existing spreadsheet files, we also provide spreadsheet template files that are pre-formatted for upload.
Raw scans are uploaded separately from your measurement spreadsheet. For each image, have the file name, sample name, bone type, and region scanned ready. Scans are publicly available for download but, because of their size, cannot be viewed in the web portal.
Prepare publication-ready figures as JPG, PNG, or WebP files up to 10 MB each. A web-resolution version is enough, and smaller files load faster. Each image needs a caption (figure legend) describing what it shows. Representative images and their captions are displayed publicly.
How Your Files Are Stored and Shared
All uploaded files, including images, are stored in their original form to ensure authenticity. Object storage keeps each file as an independent object — easily accessed, retrieved, and managed — without altering the original content.
During upload, your spreadsheet data is also ingested into a PostgreSQL database. This enables efficient searching through the ROSSA datacenter and programmatic access via the API.
Your original data files will be publicly accessible to users browsing the datacenter. This includes microCT scans, which are available for download but not for viewing in the web portal. Please ensure the contents of your files are presentable and clearly organized before uploading.
File Validation
To ensure your data is accurately read and annotated, each spreadsheet enters a validation viewer that provides human-in-the-loop review.
During validation you will:
- Confirm or correct matched measurement parameters
- Annotate individual animals into their respective groupings (e.g. control vs. experimental)
Example: Parameter Matching
| Spreadsheet Header | ROSSA Match | |
|---|---|---|
| Tt.Ar mm^2 | Total Area (mm²) |
|
| Ct.Ar mm^2 | Cortical Area (mm²) |
|
| Ps.Pm mm | Periosteal Perimeter (mm) |
|
| Po.N | Pore Number (n) |
Ready to get started?
The process is straightforward and you can save your progress at any time.
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