Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Adora2b KO Male
M
12wk
B6N(Cg)-Adora2b tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Adora2b KO Female
F
12wk
B6N(Cg)-Adora2b tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Adora2b WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Adora2b WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Adora2b WT Male (Mean ± SD) | Adora2b KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 23.90 ± 1.25 | 25.01 ± 2.08 | 0.2581 |
| Bone Mineral Density (mg/ccm HA) | 1,131.29 ± 4.88 | 1,108.02 ± 6.70 | <0.001* |
| Cortical Area (mm^2) | 0.668 ± 0.040 | 0.652 ± 0.035 | 0.4642 |
| Cortical Area / Total Area (%) | 41.12 ± 1.23 | 38.52 ± 1.90 | 0.0110* |
| Cortical Mask (dimensionless) | 0.670 ± 0.041 | 0.655 ± 0.036 | 0.4943 |
| Cortical Porosity (%) | 0.334 ± 0.055 | 0.487 ± 0.088 | 0.0022* |
| Cortical Thickness (mm) | 0.1568 ± 0.0071 | 0.1489 ± 0.0081 | 0.0831 |
| Endocortical Perimeter (mm) | 3.459 ± 0.061 | 3.609 ± 0.079 | 0.0020* |
| Length (mm) | 14.35 ± 0.17 | 14.50 ± 0.24 | 0.2143 |
| Marrow Area (mm^2) | 0.953 ± 0.033 | 1.037 ± 0.045 | 0.0020* |
| Maximum Distance from Centroid (mm) | 1.875 ± 0.065 | 1.891 ± 0.054 | 0.6355 |
| Maximum Moment of Inertia (mm^4) | 0.201 ± 0.019 | 0.203 ± 0.015 | 0.8869 |
| Minimum Distance from Centroid (mm) | 1.188 ± 0.022 | 1.219 ± 0.014 | 0.0108* |
| Minimum Moment of Inertia (mm^4) | 0.0946 ± 0.0083 | 0.0997 ± 0.0056 | 0.2237 |
| Periosteal Perimeter (mm) | 4.51 ± 0.10 | 4.46 ± 0.11 | 0.4024 |
| Polar Moment of Inertia (mm^4) | 0.296 ± 0.027 | 0.302 ± 0.020 | 0.6363 |
| Pore Area (mm^2) | 0.0023 ± 0.0004 | 0.0032 ± 0.0006 | 0.0077* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.214 ± 0.014 | 0.214 ± 0.011 | 0.9813 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.159 ± 0.012 | 0.1636 ± 0.0092 | 0.4544 |
| Tissue Mineral Density (mg/ccm HA) | 1,205.54 ± 5.10 | 1,187.57 ± 5.98 | <0.001* |
| Total Area (mm^2) | 1.622 ± 0.065 | 1.692 ± 0.047 | 0.0484* |