Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Hsf4 KO Male
M
12wk
B6N(Cg)-Hsf4 tm1b(KOMP)Wtsi/J (C57BL/6NTac)
• KO/KO
Hsf4 KO Female
F
12wk
B6N(Cg)-Hsf4 tm1b(KOMP)Wtsi/J (C57BL/6NTac)
• KO/KO
Hsf4 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Hsf4 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Hsf4 WT Male (Mean ± SD) | Hsf4 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 28.75 ± 3.22 | 27.42 ± 2.01 | 0.3468 |
| Bone Mineral Density (mg/ccm HA) | 1,101.41 ± 3.33 | 1,107.42 ± 7.09 | 0.0574 |
| Cortical Area (mm^2) | 0.805 ± 0.065 | 0.743 ± 0.084 | 0.1401 |
| Cortical Area / Total Area (%) | 39.82 ± 0.56 | 40.10 ± 1.77 | 0.6896 |
| Cortical Mask (dimensionless) | 0.808 ± 0.066 | 0.746 ± 0.085 | 0.1401 |
| Cortical Porosity (%) | 0.43 ± 0.11 | 0.401 ± 0.085 | 0.5815 |
| Cortical Thickness (mm) | 0.1710 ± 0.0091 | 0.163 ± 0.012 | 0.1611 |
| Endocortical Perimeter (mm) | 3.90 ± 0.14 | 3.72 ± 0.18 | 0.0528 |
| Length (mm) | 14.86 ± 0.20 | 14.72 ± 0.27 | 0.2798 |
| Marrow Area (mm^2) | 1.212 ± 0.086 | 1.11 ± 0.10 | 0.0520 |
| Maximum Distance from Centroid (mm) | 2.078 ± 0.075 | 2.00 ± 0.11 | 0.1144 |
| Maximum Moment of Inertia (mm^4) | 0.298 ± 0.040 | 0.254 ± 0.051 | 0.0863 |
| Minimum Distance from Centroid (mm) | 1.344 ± 0.081 | 1.262 ± 0.064 | 0.0446* |
| Minimum Moment of Inertia (mm^4) | 0.147 ± 0.026 | 0.125 ± 0.026 | 0.1135 |
| Periosteal Perimeter (mm) | 5.09 ± 0.20 | 4.89 ± 0.27 | 0.1273 |
| Polar Moment of Inertia (mm^4) | 0.445 ± 0.063 | 0.379 ± 0.076 | 0.0897 |
| Pore Area (mm^2) | 0.0035 ± 0.0011 | 0.0030 ± 0.0008 | 0.3180 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.286 ± 0.030 | 0.253 ± 0.037 | 0.0811 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.218 ± 0.026 | 0.196 ± 0.032 | 0.1806 |
| Tissue Mineral Density (mg/ccm HA) | 1,163.01 ± 5.05 | 1,173.15 ± 7.54 | 0.0086* |
| Total Area (mm^2) | 2.02 ± 0.15 | 1.85 ± 0.18 | 0.0712 |