Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Bhlhe40 KO Male
M
12wk
B6N(Cg)-Bhlhe40<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Bhlhe40 KO Female
F
12wk
B6N(Cg)-Bhlhe40<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Bhlhe40 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Bhlhe40 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Bhlhe40 WT Male (Mean ± SD) | Bhlhe40 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.83 ± 3.50 | 23.24 ± 3.02 | 0.4012 |
| Bone Mineral Density (mg/ccm HA) | 1,143.37 ± 7.98 | 1,143.56 ± 7.78 | 0.9644 |
| Cortical Area (mm^2) | 0.646 ± 0.037 | 0.721 ± 0.079 | 0.0391* |
| Cortical Area / Total Area (%) | 41.03 ± 2.71 | 37.77 ± 1.08 | 0.0103* |
| Cortical Mask (dimensionless) | 0.648 ± 0.037 | 0.723 ± 0.079 | 0.0394* |
| Cortical Porosity (%) | 0.252 ± 0.023 | 0.248 ± 0.035 | 0.8173 |
| Cortical Thickness (mm) | 0.1559 ± 0.0050 | 0.1550 ± 0.0085 | 0.8129 |
| Endocortical Perimeter (mm) | 3.42 ± 0.26 | 3.86 ± 0.25 | 0.0067* |
| Length (mm) | 14.56 ± 0.27 | 14.49 ± 0.44 | 0.7079 |
| Marrow Area (mm^2) | 0.94 ± 0.14 | 1.19 ± 0.15 | 0.0062* |
| Maximum Distance from Centroid (mm) | 1.80 ± 0.14 | 1.97 ± 0.16 | 0.0613 |
| Maximum Moment of Inertia (mm^4) | 0.188 ± 0.038 | 0.253 ± 0.058 | 0.0267* |
| Minimum Distance from Centroid (mm) | 1.192 ± 0.035 | 1.314 ± 0.049 | <0.001* |
| Minimum Moment of Inertia (mm^4) | 0.093 ± 0.015 | 0.130 ± 0.027 | 0.0068* |
| Periosteal Perimeter (mm) | 4.31 ± 0.43 | 4.76 ± 0.50 | 0.0894 |
| Polar Moment of Inertia (mm^4) | 0.281 ± 0.053 | 0.383 ± 0.084 | 0.0168* |
| Pore Area (mm^2) | 0.0016 ± 0.0002 | 0.0018 ± 0.0004 | 0.3168 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.206 ± 0.028 | 0.254 ± 0.041 | 0.0232* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.156 ± 0.021 | 0.198 ± 0.035 | 0.0171* |
| Tissue Mineral Density (mg/ccm HA) | 1,208.83 ± 9.14 | 1,207.89 ± 8.65 | 0.8463 |
| Total Area (mm^2) | 1.59 ± 0.18 | 1.91 ± 0.22 | 0.0090* |