Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Nek11 KO Male
M
12wk
B6N(Cg)-Nek11<tm1b(KOMP)Wtsi/J (C57BL/6NTac)
• KO/KO
Nek11 KO Female
F
12wk
B6N(Cg)-Nek11<tm1b(KOMP)Wtsi/J (C57BL/6NTac)
• KO/KO
Nek11 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Nek11 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Nek11 WT Male (Mean ± SD) | Nek11 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.47 ± 1.55 | 23.35 ± 2.32 | 0.3316 |
| Bone Mineral Density (mg/ccm HA) | 1,131.94 ± 7.26 | 1,140.55 ± 6.33 | 0.0330* |
| Cortical Area (mm^2) | 0.648 ± 0.027 | 0.683 ± 0.050 | 0.1309 |
| Cortical Area / Total Area (%) | 38.74 ± 1.20 | 40.24 ± 1.64 | 0.0723 |
| Cortical Mask (dimensionless) | 0.650 ± 0.028 | 0.685 ± 0.050 | 0.1262 |
| Cortical Porosity (%) | 0.260 ± 0.017 | 0.325 ± 0.036 | <0.001* |
| Cortical Thickness (mm) | 0.1493 ± 0.0050 | 0.1577 ± 0.0095 | 0.0563 |
| Endocortical Perimeter (mm) | 3.586 ± 0.088 | 3.564 ± 0.079 | 0.6183 |
| Length (mm) | 14.56 ± 0.15 | 14.70 ± 0.13 | 0.1081 |
| Marrow Area (mm^2) | 1.024 ± 0.050 | 1.011 ± 0.044 | 0.6123 |
| Maximum Distance from Centroid (mm) | 1.858 ± 0.051 | 1.884 ± 0.080 | 0.4825 |
| Maximum Moment of Inertia (mm^4) | 0.196 ± 0.016 | 0.212 ± 0.026 | 0.1803 |
| Minimum Distance from Centroid (mm) | 1.221 ± 0.037 | 1.224 ± 0.028 | 0.8499 |
| Minimum Moment of Inertia (mm^4) | 0.1008 ± 0.0074 | 0.104 ± 0.010 | 0.5179 |
| Periosteal Perimeter (mm) | 4.44 ± 0.16 | 4.50 ± 0.14 | 0.4660 |
| Polar Moment of Inertia (mm^4) | 0.297 ± 0.022 | 0.316 ± 0.035 | 0.2410 |
| Pore Area (mm^2) | 0.0017 ± 0.0001 | 0.0022 ± 0.0002 | <0.001* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.211 ± 0.012 | 0.225 ± 0.020 | 0.1407 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.1651 ± 0.0086 | 0.170 ± 0.015 | 0.4889 |
| Tissue Mineral Density (mg/ccm HA) | 1,198.58 ± 7.48 | 1,206.79 ± 6.95 | 0.0515 |
| Total Area (mm^2) | 1.674 ± 0.066 | 1.696 ± 0.080 | 0.5790 |