Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Prokr1 KO Male
M
12wk
B6N(Cg)-Prokr1 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Prokr1 KO Female
F
12wk
B6N(Cg)-Prokr1 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Prokr1 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Prokr1 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Prokr1 WT Male (Mean ± SD) | Prokr1 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Bone Mineral Density (mg/ccm HA) | 1,111.54 ± 3.34 | 1,144.47 ± 13.47 | <0.001* |
| Cortical Area (mm^2) | 0.747 ± 0.045 | 0.688 ± 0.046 | 0.0468* |
| Cortical Area / Total Area (%) | 41.52 ± 1.32 | 37.28 ± 1.27 | <0.001* |
| Cortical Mask (dimensionless) | 0.749 ± 0.045 | 0.691 ± 0.048 | 0.0525 |
| Cortical Porosity (%) | 0.358 ± 0.049 | 0.42 ± 0.26 | 0.5811 |
| Cortical Thickness (mm) | 0.1689 ± 0.0055 | 0.1500 ± 0.0068 | <0.001* |
| Endocortical Perimeter (mm) | 3.63 ± 0.14 | 3.81 ± 0.16 | 0.0610 |
| Length (mm) | 14.79 ± 0.15 | 14.47 ± 0.36 | 0.0535 |
| Marrow Area (mm^2) | 1.050 ± 0.080 | 1.156 ± 0.097 | 0.0616 |
| Maximum Distance from Centroid (mm) | 1.971 ± 0.054 | 1.941 ± 0.064 | 0.3984 |
| Maximum Moment of Inertia (mm^4) | 0.246 ± 0.028 | 0.223 ± 0.036 | 0.2326 |
| Minimum Distance from Centroid (mm) | 1.257 ± 0.056 | 1.354 ± 0.066 | 0.0174* |
| Minimum Moment of Inertia (mm^4) | 0.118 ± 0.015 | 0.125 ± 0.018 | 0.4716 |
| Periosteal Perimeter (mm) | 4.76 ± 0.17 | 4.66 ± 0.35 | 0.5133 |
| Polar Moment of Inertia (mm^4) | 0.364 ± 0.043 | 0.348 ± 0.052 | 0.5677 |
| Pore Area (mm^2) | 0.0027 ± 0.0005 | 0.0030 ± 0.0022 | 0.7442 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.249 ± 0.023 | 0.229 ± 0.029 | 0.1919 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.188 ± 0.017 | 0.185 ± 0.020 | 0.7815 |
| Tissue Mineral Density (mg/ccm HA) | 1,175.23 ± 3.91 | 1,208.55 ± 15.00 | <0.001* |
| Total Area (mm^2) | 1.80 ± 0.12 | 1.85 ± 0.14 | 0.5366 |