Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Hemgn KO Male
M
12wk
B6N(Cg)-Hemgn<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Hemgn KO Female
F
12wk
B6N(Cg)-Hemgn<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Hemgn WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Hemgn WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Hemgn WT Male (Mean ± SD) | Hemgn KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 28.21 ± 2.11 | 25.45 ± 1.67 | 0.0166* |
| Bone Mineral Density (mg/ccm HA) | 1,135.37 ± 9.56 | 1,145.14 ± 8.16 | 0.0589 |
| Cortical Area (mm^2) | 0.685 ± 0.059 | 0.798 ± 0.097 | 0.0201* |
| Cortical Area / Total Area (%) | 38.71 ± 1.21 | 40.75 ± 1.72 | 0.0222* |
| Cortical Mask (dimensionless) | 0.687 ± 0.059 | 0.800 ± 0.098 | 0.0199* |
| Cortical Porosity (%) | 0.249 ± 0.026 | 0.299 ± 0.053 | 0.0415* |
| Cortical Thickness (mm) | 0.154 ± 0.011 | 0.172 ± 0.017 | 0.0340* |
| Endocortical Perimeter (mm) | 3.69 ± 0.14 | 3.80 ± 0.18 | 0.1936 |
| Length (mm) | 14.74 ± 0.22 | 14.87 ± 0.25 | 0.3166 |
| Marrow Area (mm^2) | 1.083 ± 0.081 | 1.15 ± 0.11 | 0.1927 |
| Maximum Distance from Centroid (mm) | 1.912 ± 0.090 | 2.018 ± 0.070 | 0.0273* |
| Maximum Moment of Inertia (mm^4) | 0.225 ± 0.038 | 0.284 ± 0.049 | 0.0250* |
| Minimum Distance from Centroid (mm) | 1.244 ± 0.046 | 1.31 ± 0.11 | 0.1726 |
| Minimum Moment of Inertia (mm^4) | 0.112 ± 0.016 | 0.143 ± 0.037 | 0.0578 |
| Periosteal Perimeter (mm) | 4.67 ± 0.29 | 4.91 ± 0.30 | 0.1429 |
| Polar Moment of Inertia (mm^4) | 0.337 ± 0.054 | 0.427 ± 0.085 | 0.0328* |
| Pore Area (mm^2) | 0.0017 ± 0.0002 | 0.0024 ± 0.0006 | 0.0220* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.234 ± 0.029 | 0.281 ± 0.041 | 0.0297* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.179 ± 0.020 | 0.215 ± 0.038 | 0.0417* |
| Tissue Mineral Density (mg/ccm HA) | 1,198.35 ± 9.97 | 1,204.84 ± 6.02 | 0.1624 |
| Total Area (mm^2) | 1.77 ± 0.13 | 1.95 ± 0.20 | 0.0621 |