Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Lcn2 KO Male
M
12wk
B6N(Cg)-Lcn2<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Lcn2 KO Female
F
12wk
B6N(Cg)-Lcn2<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Lcn2 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Lcn2 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Lcn2 WT Male (Mean ± SD) | Lcn2 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 27.96 ± 2.30 | 27.33 ± 2.77 | 0.6508 |
| Bone Mineral Density (mg/ccm HA) | 1,132.80 ± 6.60 | 1,142.37 ± 11.90 | 0.0840 |
| Cortical Area (mm^2) | 0.679 ± 0.063 | 0.746 ± 0.050 | 0.0448* |
| Cortical Area / Total Area (%) | 38.38 ± 0.97 | 40.63 ± 1.21 | 0.0018* |
| Cortical Mask (dimensionless) | 0.681 ± 0.063 | 0.748 ± 0.051 | 0.0448* |
| Cortical Porosity (%) | 0.251 ± 0.025 | 0.250 ± 0.034 | 0.9325 |
| Cortical Thickness (mm) | 0.153 ± 0.012 | 0.1652 ± 0.0091 | 0.0379* |
| Endocortical Perimeter (mm) | 3.69 ± 0.13 | 3.696 ± 0.092 | 0.9794 |
| Length (mm) | 14.75 ± 0.21 | 14.72 ± 0.11 | 0.7412 |
| Marrow Area (mm^2) | 1.087 ± 0.076 | 1.087 ± 0.054 | 0.9938 |
| Maximum Distance from Centroid (mm) | 1.918 ± 0.087 | 1.989 ± 0.077 | 0.1254 |
| Maximum Moment of Inertia (mm^4) | 0.224 ± 0.039 | 0.252 ± 0.027 | 0.1377 |
| Minimum Distance from Centroid (mm) | 1.239 ± 0.049 | 1.263 ± 0.052 | 0.3842 |
| Minimum Moment of Inertia (mm^4) | 0.110 ± 0.017 | 0.123 ± 0.016 | 0.1806 |
| Periosteal Perimeter (mm) | 4.67 ± 0.29 | 4.72 ± 0.17 | 0.7485 |
| Polar Moment of Inertia (mm^4) | 0.334 ± 0.056 | 0.375 ± 0.040 | 0.1415 |
| Pore Area (mm^2) | 0.0017 ± 0.0002 | 0.0019 ± 0.0003 | 0.2617 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.232 ± 0.031 | 0.253 ± 0.020 | 0.1582 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.178 ± 0.021 | 0.194 ± 0.017 | 0.1392 |
| Tissue Mineral Density (mg/ccm HA) | 1,195.97 ± 6.58 | 1,201.59 ± 15.09 | 0.3823 |
| Total Area (mm^2) | 1.77 ± 0.14 | 1.836 ± 0.096 | 0.2994 |