Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Dennd2d KO Male
M
12wk
B6N(Cg)-Dennd2d<tm2b(KOMP)Mbp>/J (C57BL/6NTac)
• KO/KO
Dennd2d KO Female
F
12wk
B6N(Cg)-Dennd2d<tm2b(KOMP)Mbp>/J (C57BL/6NTac)
• KO/KO
Dennd2d WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Dennd2d WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Dennd2d WT Male (Mean ± SD) | Dennd2d KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 25.33 ± 1.81 | 25.30 ± 2.04 | 0.9819 |
| Bone Mineral Density (mg/ccm HA) | 1,138.32 ± 8.77 | 1,146.51 ± 2.26 | 0.0440* |
| Cortical Area (mm^2) | 0.722 ± 0.084 | 0.704 ± 0.053 | 0.6274 |
| Cortical Area / Total Area (%) | 39.64 ± 1.11 | 39.69 ± 0.87 | 0.9291 |
| Cortical Mask (dimensionless) | 0.724 ± 0.085 | 0.705 ± 0.054 | 0.6302 |
| Cortical Porosity (%) | 0.242 ± 0.041 | 0.260 ± 0.039 | 0.4254 |
| Cortical Thickness (mm) | 0.161 ± 0.012 | 0.1585 ± 0.0091 | 0.7172 |
| Endocortical Perimeter (mm) | 3.71 ± 0.21 | 3.66 ± 0.11 | 0.5895 |
| Length (mm) | 12.98 ± 4.92 | 14.74 ± 0.16 | 0.3605 |
| Marrow Area (mm^2) | 1.10 ± 0.12 | 1.066 ± 0.061 | 0.5567 |
| Maximum Distance from Centroid (mm) | 1.96 ± 0.12 | 1.924 ± 0.087 | 0.5031 |
| Maximum Moment of Inertia (mm^4) | 0.242 ± 0.056 | 0.226 ± 0.032 | 0.5327 |
| Minimum Distance from Centroid (mm) | 1.268 ± 0.078 | 1.245 ± 0.036 | 0.4923 |
| Minimum Moment of Inertia (mm^4) | 0.122 ± 0.026 | 0.115 ± 0.014 | 0.5407 |
| Periosteal Perimeter (mm) | 4.73 ± 0.41 | 4.58 ± 0.28 | 0.4405 |
| Polar Moment of Inertia (mm^4) | 0.363 ± 0.081 | 0.341 ± 0.046 | 0.5297 |
| Pore Area (mm^2) | 0.0018 ± 0.0004 | 0.0018 ± 0.0004 | 0.7106 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.244 ± 0.042 | 0.234 ± 0.024 | 0.6052 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.190 ± 0.030 | 0.184 ± 0.017 | 0.6328 |
| Tissue Mineral Density (mg/ccm HA) | 1,200.93 ± 6.97 | 1,212.04 ± 3.76 | 0.0023* |
| Total Area (mm^2) | 1.82 ± 0.20 | 1.77 ± 0.11 | 0.5781 |