Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Abca7 KO Male
M
12wk
B6N(Cg)-Abca7<tm2b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Abca7 KO Female
F
12wk
B6N(Cg)-Abca7<tm2b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Abca7 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Abca7 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Abca7 WT Male (Mean ± SD) | Abca7 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 25.33 ± 1.81 | 24.14 ± 2.85 | 0.3827 |
| Bone Mineral Density (mg/ccm HA) | 1,138.32 ± 8.77 | 1,145.32 ± 18.71 | 0.3949 |
| Cortical Area (mm^2) | 0.722 ± 0.084 | 0.69 ± 0.15 | 0.6609 |
| Cortical Area / Total Area (%) | 39.64 ± 1.11 | 39.08 ± 2.47 | 0.5995 |
| Cortical Mask (dimensionless) | 0.724 ± 0.085 | 0.70 ± 0.15 | 0.6732 |
| Cortical Porosity (%) | 0.242 ± 0.041 | 0.36 ± 0.14 | 0.0504 |
| Cortical Thickness (mm) | 0.161 ± 0.012 | 0.158 ± 0.023 | 0.7580 |
| Endocortical Perimeter (mm) | 3.71 ± 0.21 | 3.65 ± 0.23 | 0.6359 |
| Length (mm) | 12.98 ± 4.92 | 14.64 ± 0.46 | 0.4212 |
| Marrow Area (mm^2) | 1.10 ± 0.12 | 1.06 ± 0.14 | 0.6471 |
| Maximum Distance from Centroid (mm) | 1.96 ± 0.12 | 1.89 ± 0.19 | 0.4418 |
| Maximum Moment of Inertia (mm^4) | 0.242 ± 0.056 | 0.235 ± 0.093 | 0.8685 |
| Minimum Distance from Centroid (mm) | 1.268 ± 0.078 | 1.243 ± 0.088 | 0.5879 |
| Minimum Moment of Inertia (mm^4) | 0.122 ± 0.026 | 0.113 ± 0.041 | 0.6530 |
| Periosteal Perimeter (mm) | 4.73 ± 0.41 | 4.64 ± 0.66 | 0.7698 |
| Polar Moment of Inertia (mm^4) | 0.363 ± 0.081 | 0.35 ± 0.13 | 0.7984 |
| Pore Area (mm^2) | 0.0018 ± 0.0004 | 0.0027 ± 0.0016 | 0.1782 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.244 ± 0.042 | 0.241 ± 0.069 | 0.9332 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.190 ± 0.030 | 0.178 ± 0.050 | 0.6161 |
| Tissue Mineral Density (mg/ccm HA) | 1,200.93 ± 6.97 | 1,213.32 ± 14.25 | 0.0635 |
| Total Area (mm^2) | 1.82 ± 0.20 | 1.76 ± 0.29 | 0.6516 |