Study Datasets
Bone Histomorphometry
1 uploads
Bone: Femur
Region: Trabecular
Bone Histomorphometry
1 uploads
Bone: Vertebra
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Tex29 KO Male
M
12wk
B6N(Cg)-Tex29<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Tex29 KO Female
F
12wk
B6N(Cg)-Tex29<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Tex29 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Tex29 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Bone Histomorphometry Bone: Femur Region: Trabecular
| Variable | Tex29 WT Male (Mean ± SD) | Tex29 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Alkaline Phosphatase+ Bone Surface/Bone Surface (AP/BS) (%) | 50.60 ± 5.88 | 9.41 ± 2.80 | <0.001* |
| Alkaline Phosphatase+ Bone Surface/Labeled Bone Surface (AP/L.BS) (%) | 29.00 ± 4.87 | 5.18 ± 1.63 | <0.001* |
| Alkaline Phosphatase+ Bone Surface/Non-Labeled Bone Surface (AP/NL.BS) (%) | 22.01 ± 3.66 | 3.99 ± 1.65 | <0.001* |
| AP+ TRAP+ Labeled Bone Surface/Bone Surface (AP+TRAP+L.BS/BS) (%) | 3.46 ± 0.48 | 0.65 ± 0.30 | <0.001* |
| Body Weight (g) | 27.49 ± 2.14 | 26.29 ± 1.07 | 0.2329 |
| Bone Formation Rate/Bone Surface (BFR/BS) (µm3/µm2/day) | 0.366 ± 0.074 | 0.297 ± 0.029 | 0.0527 |
| Bone Volume/Tissue Volume (BV/TV) (%) | 13.61 ± 1.37 | 15.90 ± 1.50 | 0.0132* |
| Labeled Alkaline Phosphatase+ Surface/Total AP+ Surface (L.S+AP/T.AP) (%) | 56.60 ± 5.31 | 56.92 ± 6.52 | 0.9282 |
| Mineral Apposition Rate (MAR) (µm/day) | 1.26 ± 0.16 | 1.303 ± 0.088 | 0.5828 |
| Mineralizing Surface/Bone Surface (MS/BS) (%) | 28.20 ± 3.69 | 22.78 ± 2.51 | 0.0091* |
| Non-Labeled Alkaline Phosphatase+ Surface/Total AP+ Surface (NL.S+AP/T.AP) (%) | 43.40 ± 5.31 | 43.08 ± 6.52 | 0.9282 |
| Trabecular Number (Tb.N) (#/mm) | 2.80 ± 0.24 | 2.76 ± 0.31 | 0.8039 |
| Trabecular Spacing (Tb.Sp) (µm) | 313.32 ± 30.86 | 311.79 ± 39.12 | 0.9383 |
| Trabecular Thickness (Tb.Th) (µm) | 47.04 ± 2.35 | 57.14 ± 4.42 | <0.001* |
| TRAP+ Bone Surface/Bone Surface (TRAP/BS) (%) | 15.93 ± 1.89 | 16.71 ± 2.77 | 0.5721 |
| TRAP+ Bone Surface/Labeled Bone Surface (TRAP/L.BS) (%) | 7.66 ± 0.89 | 6.48 ± 1.97 | 0.1867 |
| TRAP+ Bone Surface/Non-Labeled Bone Surface (TRAP/NL.BS) (%) | 8.00 ± 1.80 | 11.08 ± 2.89 | 0.0427* |
| TRAP+ Bone Surface/Total TRAP+ Surface (TRAP/TRAP) (%) | 86.91 ± 3.57 | 86.58 ± 4.46 | 0.8887 |
| TRAP+ Labeled Bone Surface/TRAP+ Bone Surface (TRAP+L.BS/TRAP.BS) (%) | 49.00 ± 6.11 | 37.04 ± 4.67 | 0.0030* |
| TRAP+ Non-Labeled Bone Surface/TRAP+ Bone Surface (TRAP+QS.BS/TRAP.BS) (%) | 51.00 ± 6.11 | 62.96 ± 4.67 | 0.0030* |