Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Macrod2 KO Male
M
12wk
B6N(Cg)-Macrod2 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Macrod2 KO Female
F
12wk
B6N(Cg)-Macrod2 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Macrod2 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Macrod2 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Macrod2 WT Male (Mean ± SD) | Macrod2 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.43 ± 1.27 | 25.72 ± 3.29 | 0.6070 |
| Bone Mineral Density (mg/ccm HA) | 1,120.13 ± 8.22 | 1,108.25 ± 8.74 | 0.0254* |
| Cortical Area (mm^2) | 0.744 ± 0.014 | 0.724 ± 0.045 | 0.3304 |
| Cortical Area / Total Area (%) | 41.44 ± 1.43 | 40.80 ± 1.28 | 0.4159 |
| Cortical Mask (dimensionless) | 0.746 ± 0.014 | 0.726 ± 0.045 | 0.3355 |
| Cortical Porosity (%) | 0.373 ± 0.077 | 0.369 ± 0.088 | 0.9387 |
| Cortical Thickness (mm) | 0.1674 ± 0.0052 | 0.1614 ± 0.0054 | 0.0658 |
| Endocortical Perimeter (mm) | 3.63 ± 0.10 | 3.63 ± 0.17 | 0.9842 |
| Length (mm) | 14.69 ± 0.12 | 14.61 ± 0.19 | 0.4090 |
| Marrow Area (mm^2) | 1.050 ± 0.060 | 1.050 ± 0.100 | 0.9899 |
| Maximum Distance from Centroid (mm) | 1.977 ± 0.041 | 1.936 ± 0.068 | 0.2157 |
| Maximum Moment of Inertia (mm^4) | 0.2484 ± 0.0088 | 0.234 ± 0.029 | 0.2860 |
| Minimum Distance from Centroid (mm) | 1.247 ± 0.038 | 1.242 ± 0.048 | 0.8341 |
| Minimum Moment of Inertia (mm^4) | 0.1154 ± 0.0077 | 0.116 ± 0.019 | 0.9410 |
| Periosteal Perimeter (mm) | 4.806 ± 0.081 | 4.75 ± 0.22 | 0.5572 |
| Polar Moment of Inertia (mm^4) | 0.364 ± 0.016 | 0.350 ± 0.048 | 0.5272 |
| Pore Area (mm^2) | 0.0028 ± 0.0006 | 0.0027 ± 0.0008 | 0.8735 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.2514 ± 0.0072 | 0.241 ± 0.022 | 0.3128 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.1849 ± 0.0075 | 0.186 ± 0.024 | 0.9157 |
| Tissue Mineral Density (mg/ccm HA) | 1,186.98 ± 9.51 | 1,173.72 ± 11.22 | 0.0382* |
| Total Area (mm^2) | 1.796 ± 0.063 | 1.78 ± 0.14 | 0.7624 |