Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Tmem181a KO Male
M
12wk
B6N(Cg)-Tmem181a<tm1b(EUCOMM)Wtsi>/J (C57BL/6NTac)
• KO/KO
Tmem181a KO Female
F
12wk
B6N(Cg)-Tmem181a<tm1b(EUCOMM)Wtsi>/J (C57BL/6NTac)
• KO/KO
Tmem181a WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Tmem181a WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Tmem181a WT Male (Mean ± SD) | Tmem181a KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Bone Mineral Density (mg/ccm HA) | 1,134.99 ± 7.75 | 1,148.11 ± 3.62 | 0.0012* |
| Cortical Area (mm^2) | 0.680 ± 0.063 | 0.767 ± 0.051 | 0.0131* |
| Cortical Area / Total Area (%) | 38.84 ± 1.31 | 40.44 ± 1.29 | 0.0365* |
| Cortical Mask (dimensionless) | 0.682 ± 0.063 | 0.769 ± 0.051 | 0.0127* |
| Cortical Porosity (%) | 0.248 ± 0.024 | 0.311 ± 0.077 | 0.0573 |
| Cortical Thickness (mm) | 0.155 ± 0.011 | 0.1674 ± 0.0066 | 0.0254* |
| Endocortical Perimeter (mm) | 3.66 ± 0.16 | 3.76 ± 0.17 | 0.2685 |
| Length (mm) | 14.74 ± 0.21 | 14.67 ± 0.22 | 0.5326 |
| Marrow Area (mm^2) | 1.069 ± 0.093 | 1.13 ± 0.10 | 0.2667 |
| Maximum Distance from Centroid (mm) | 1.911 ± 0.089 | 2.033 ± 0.052 | 0.0075* |
| Maximum Moment of Inertia (mm^4) | 0.223 ± 0.039 | 0.274 ± 0.032 | 0.0194* |
| Minimum Distance from Centroid (mm) | 1.237 ± 0.050 | 1.281 ± 0.070 | 0.2024 |
| Minimum Moment of Inertia (mm^4) | 0.109 ± 0.019 | 0.128 ± 0.022 | 0.0869 |
| Periosteal Perimeter (mm) | 4.64 ± 0.31 | 4.86 ± 0.30 | 0.2087 |
| Polar Moment of Inertia (mm^4) | 0.332 ± 0.057 | 0.402 ± 0.052 | 0.0312* |
| Pore Area (mm^2) | 0.0017 ± 0.0002 | 0.0024 ± 0.0006 | 0.0147* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.232 ± 0.031 | 0.268 ± 0.025 | 0.0302* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.175 ± 0.024 | 0.199 ± 0.023 | 0.0700 |
| Tissue Mineral Density (mg/ccm HA) | 1,198.45 ± 8.55 | 1,210.88 ± 5.85 | 0.0067* |
| Total Area (mm^2) | 1.75 ± 0.15 | 1.90 ± 0.14 | 0.0805 |