Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Hdac10 KO Male
M
12wk
B6N(Cg)-Hdac10 tm1.1(KOMP)Mbp/J (C57BL/6NTac)
• KO/KO
Hdac10 KO Female
F
12wk
B6N(Cg)-Hdac10 tm1.1(KOMP)Mbp/J (C57BL/6NTac)
• KO/KO
Hdac10 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Hdac10 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Hdac10 WT Male (Mean ± SD) | Hdac10 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.54 ± 1.53 | 24.70 ± 0.62 | 0.0105* |
| Bone Mineral Density (mg/ccm HA) | 1,132.96 ± 9.79 | 1,121.03 ± 5.57 | 0.0141* |
| Cortical Area (mm^2) | 0.712 ± 0.054 | 0.755 ± 0.036 | 0.0962 |
| Cortical Area / Total Area (%) | 40.34 ± 1.83 | 39.96 ± 1.47 | 0.6802 |
| Cortical Mask (dimensionless) | 0.714 ± 0.054 | 0.758 ± 0.035 | 0.0924 |
| Cortical Porosity (%) | 0.316 ± 0.046 | 0.382 ± 0.066 | 0.0475* |
| Cortical Thickness (mm) | 0.161 ± 0.011 | 0.1653 ± 0.0061 | 0.4002 |
| Endocortical Perimeter (mm) | 3.63 ± 0.11 | 3.77 ± 0.14 | 0.0507 |
| Length (mm) | 14.64 ± 0.15 | 14.59 ± 0.11 | 0.4820 |
| Marrow Area (mm^2) | 1.050 ± 0.062 | 1.134 ± 0.082 | 0.0490* |
| Maximum Distance from Centroid (mm) | 1.939 ± 0.069 | 1.940 ± 0.081 | 0.9979 |
| Maximum Moment of Inertia (mm^4) | 0.232 ± 0.030 | 0.255 ± 0.025 | 0.1415 |
| Minimum Distance from Centroid (mm) | 1.246 ± 0.044 | 1.307 ± 0.043 | 0.0192* |
| Minimum Moment of Inertia (mm^4) | 0.112 ± 0.012 | 0.131 ± 0.013 | 0.0122* |
| Periosteal Perimeter (mm) | 4.71 ± 0.14 | 4.88 ± 0.15 | 0.0468* |
| Polar Moment of Inertia (mm^4) | 0.343 ± 0.042 | 0.386 ± 0.038 | 0.0638 |
| Pore Area (mm^2) | 0.0023 ± 0.0004 | 0.0029 ± 0.0004 | 0.0114* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.238 ± 0.024 | 0.262 ± 0.017 | 0.0480* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.179 ± 0.015 | 0.201 ± 0.015 | 0.0170* |
| Tissue Mineral Density (mg/ccm HA) | 1,204.23 ± 6.80 | 1,187.44 ± 5.11 | <0.001* |
| Total Area (mm^2) | 1.765 ± 0.097 | 1.89 ± 0.11 | 0.0342* |