Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Ptpn5 KO Male
M
12wk
B6N(Cg)-Ptpn5<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Ptpn5 KO Female
F
12wk
B6N(Cg)-Ptpn5<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Ptpn5 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Ptpn5 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Ptpn5 WT Male (Mean ± SD) | Ptpn5 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.60 ± 2.00 | 24.82 ± 2.55 | 0.1698 |
| Bone Mineral Density (mg/ccm HA) | 1,140.51 ± 6.23 | 1,147.46 ± 8.64 | 0.1066 |
| Cortical Area (mm^2) | 0.648 ± 0.011 | 0.776 ± 0.061 | <0.001* |
| Cortical Area / Total Area (%) | 39.75 ± 0.81 | 40.08 ± 2.06 | 0.7055 |
| Cortical Mask (dimensionless) | 0.649 ± 0.011 | 0.778 ± 0.061 | <0.001* |
| Cortical Porosity (%) | 0.252 ± 0.033 | 0.327 ± 0.066 | 0.0164* |
| Cortical Thickness (mm) | 0.1506 ± 0.0037 | 0.1719 ± 0.0079 | <0.001* |
| Endocortical Perimeter (mm) | 3.510 ± 0.072 | 3.82 ± 0.27 | 0.0182* |
| Length (mm) | 14.60 ± 0.11 | 15.00 ± 0.33 | 0.0150* |
| Marrow Area (mm^2) | 0.981 ± 0.040 | 1.17 ± 0.16 | 0.0182* |
| Maximum Distance from Centroid (mm) | 1.845 ± 0.049 | 2.01 ± 0.14 | 0.0087* |
| Maximum Moment of Inertia (mm^4) | 0.1943 ± 0.0093 | 0.282 ± 0.054 | 0.0036* |
| Minimum Distance from Centroid (mm) | 1.185 ± 0.026 | 1.321 ± 0.067 | <0.001* |
| Minimum Moment of Inertia (mm^4) | 0.0952 ± 0.0050 | 0.136 ± 0.026 | 0.0040* |
| Periosteal Perimeter (mm) | 4.39 ± 0.11 | 4.97 ± 0.45 | 0.0107* |
| Polar Moment of Inertia (mm^4) | 0.290 ± 0.014 | 0.417 ± 0.079 | 0.0036* |
| Pore Area (mm^2) | 0.0016 ± 0.0002 | 0.0025 ± 0.0005 | <0.001* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.2107 ± 0.0073 | 0.277 ± 0.037 | 0.0018* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.1607 ± 0.0062 | 0.204 ± 0.029 | 0.0052* |
| Tissue Mineral Density (mg/ccm HA) | 1,206.41 ± 6.42 | 1,209.55 ± 8.75 | 0.4564 |
| Total Area (mm^2) | 1.630 ± 0.047 | 1.94 ± 0.21 | 0.0057* |