Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Thsd1 KO Male
M
12wk
B6N(Cg)-Thsd1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Thsd1 KO Female
F
12wk
B6N(Cg)-Thsd1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Thsd1 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Thsd1 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Thsd1 WT Male (Mean ± SD) | Thsd1 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.74 ± 1.76 | 23.88 ± 1.60 | 0.0066* |
| Bone Mineral Density (mg/ccm HA) | 1,156.75 ± 10.53 | 1,152.64 ± 4.85 | 0.3645 |
| Cortical Area (mm^2) | 0.792 ± 0.084 | 0.756 ± 0.088 | 0.4462 |
| Cortical Area / Total Area (%) | 41.31 ± 2.11 | 41.44 ± 0.90 | 0.8872 |
| Cortical Mask (dimensionless) | 0.794 ± 0.084 | 0.758 ± 0.089 | 0.4413 |
| Cortical Porosity (%) | 0.34 ± 0.13 | 0.279 ± 0.086 | 0.3013 |
| Cortical Thickness (mm) | 0.174 ± 0.014 | 0.169 ± 0.013 | 0.4883 |
| Endocortical Perimeter (mm) | 3.75 ± 0.21 | 3.65 ± 0.20 | 0.3922 |
| Length (mm) | 15.01 ± 0.28 | 14.82 ± 0.36 | 0.2695 |
| Marrow Area (mm^2) | 1.12 ± 0.13 | 1.07 ± 0.12 | 0.4029 |
| Maximum Distance from Centroid (mm) | 2.00 ± 0.10 | 1.932 ± 0.095 | 0.2030 |
| Maximum Moment of Inertia (mm^4) | 0.271 ± 0.053 | 0.243 ± 0.046 | 0.3145 |
| Minimum Distance from Centroid (mm) | 1.322 ± 0.087 | 1.292 ± 0.099 | 0.5593 |
| Minimum Moment of Inertia (mm^4) | 0.141 ± 0.033 | 0.129 ± 0.034 | 0.5254 |
| Periosteal Perimeter (mm) | 4.97 ± 0.34 | 4.71 ± 0.40 | 0.2196 |
| Polar Moment of Inertia (mm^4) | 0.412 ± 0.086 | 0.372 ± 0.080 | 0.3879 |
| Pore Area (mm^2) | 0.0027 ± 0.0009 | 0.0022 ± 0.0009 | 0.2791 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.269 ± 0.038 | 0.251 ± 0.038 | 0.3809 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.211 ± 0.033 | 0.197 ± 0.037 | 0.4780 |
| Tissue Mineral Density (mg/ccm HA) | 1,219.11 ± 8.48 | 1,215.66 ± 7.57 | 0.4362 |
| Total Area (mm^2) | 1.92 ± 0.20 | 1.82 ± 0.21 | 0.3970 |