Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Htr1f KO Male
M
12wk
B6N(Cg)-Htr1f<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Htr1f KO Female
F
12wk
B6N(Cg)-Htr1f<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Htr1f WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Htr1f WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Htr1f WT Male (Mean ± SD) | Htr1f KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 25.53 ± 1.98 | 28.54 ± 1.62 | 0.0077* |
| Bone Mineral Density (mg/ccm HA) | 1,162.05 ± 10.37 | 1,160.51 ± 7.04 | 0.7512 |
| Cortical Area (mm^2) | 0.748 ± 0.082 | 0.804 ± 0.042 | 0.1303 |
| Cortical Area / Total Area (%) | 43.25 ± 1.57 | 42.41 ± 1.45 | 0.3141 |
| Cortical Mask (dimensionless) | 0.750 ± 0.082 | 0.807 ± 0.042 | 0.1266 |
| Cortical Porosity (%) | 0.253 ± 0.019 | 0.34 ± 0.13 | 0.1168 |
| Cortical Thickness (mm) | 0.171 ± 0.013 | 0.1760 ± 0.0075 | 0.4066 |
| Endocortical Perimeter (mm) | 3.50 ± 0.15 | 3.70 ± 0.11 | 0.0118* |
| Length (mm) | 14.76 ± 0.23 | 14.91 ± 0.10 | 0.1484 |
| Marrow Area (mm^2) | 0.977 ± 0.081 | 1.090 ± 0.062 | 0.0109* |
| Maximum Distance from Centroid (mm) | 1.91 ± 0.10 | 2.028 ± 0.047 | 0.0144* |
| Maximum Moment of Inertia (mm^4) | 0.230 ± 0.043 | 0.277 ± 0.023 | 0.0222* |
| Minimum Distance from Centroid (mm) | 1.237 ± 0.060 | 1.288 ± 0.034 | 0.0667 |
| Minimum Moment of Inertia (mm^4) | 0.116 ± 0.022 | 0.135 ± 0.014 | 0.0796 |
| Periosteal Perimeter (mm) | 4.55 ± 0.27 | 4.86 ± 0.14 | 0.0179* |
| Polar Moment of Inertia (mm^4) | 0.346 ± 0.064 | 0.411 ± 0.036 | 0.0342* |
| Pore Area (mm^2) | 0.0019 ± 0.0003 | 0.0027 ± 0.0011 | 0.0797 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.239 ± 0.034 | 0.273 ± 0.019 | 0.0385* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.187 ± 0.026 | 0.209 ± 0.017 | 0.0848 |
| Tissue Mineral Density (mg/ccm HA) | 1,224.85 ± 9.37 | 1,222.93 ± 8.83 | 0.6988 |
| Total Area (mm^2) | 1.73 ± 0.16 | 1.896 ± 0.090 | 0.0256* |