Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Gramd1c KO Male
M
12wk
B6N(Cg)-Gramd1c<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Gramd1c KO Female
F
12wk
B6N(Cg)-Gramd1c<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Gramd1c WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Gramd1c WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Gramd1c WT Male (Mean ± SD) | Gramd1c KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.70 ± 1.14 | 26.25 ± 1.07 | 0.0208* |
| Bone Mineral Density (mg/ccm HA) | 1,143.05 ± 4.30 | 1,140.34 ± 9.41 | 0.5049 |
| Cortical Area (mm^2) | 0.679 ± 0.053 | 0.746 ± 0.054 | 0.0349* |
| Cortical Area / Total Area (%) | 40.80 ± 1.11 | 39.58 ± 1.71 | 0.1365 |
| Cortical Mask (dimensionless) | 0.681 ± 0.053 | 0.748 ± 0.054 | 0.0347* |
| Cortical Porosity (%) | 0.246 ± 0.032 | 0.258 ± 0.037 | 0.5022 |
| Cortical Thickness (mm) | 0.1575 ± 0.0089 | 0.162 ± 0.011 | 0.3915 |
| Endocortical Perimeter (mm) | 3.513 ± 0.087 | 3.777 ± 0.052 | <0.001* |
| Length (mm) | 14.64 ± 0.13 | 14.80 ± 0.24 | 0.1454 |
| Marrow Area (mm^2) | 0.983 ± 0.049 | 1.135 ± 0.031 | <0.001* |
| Maximum Distance from Centroid (mm) | 1.873 ± 0.086 | 1.990 ± 0.032 | 0.0046* |
| Maximum Moment of Inertia (mm^4) | 0.209 ± 0.030 | 0.256 ± 0.024 | 0.0053* |
| Minimum Distance from Centroid (mm) | 1.190 ± 0.030 | 1.288 ± 0.045 | <0.001* |
| Minimum Moment of Inertia (mm^4) | 0.101 ± 0.013 | 0.128 ± 0.013 | 0.0015* |
| Periosteal Perimeter (mm) | 4.44 ± 0.18 | 4.85 ± 0.15 | <0.001* |
| Polar Moment of Inertia (mm^4) | 0.309 ± 0.042 | 0.384 ± 0.036 | 0.0030* |
| Pore Area (mm^2) | 0.0017 ± 0.0003 | 0.0019 ± 0.0003 | 0.1232 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.222 ± 0.022 | 0.257 ± 0.021 | 0.0092* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.169 ± 0.017 | 0.198 ± 0.016 | 0.0049* |
| Tissue Mineral Density (mg/ccm HA) | 1,206.85 ± 3.48 | 1,202.03 ± 8.22 | 0.1751 |
| Total Area (mm^2) | 1.664 ± 0.097 | 1.883 ± 0.068 | <0.001* |