Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Iqgap2 KO Male
M
12wk
B6N(Cg)-Iqgap2<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Iqgap2 KO Female
F
12wk
B6N(Cg)-Iqgap2<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Iqgap2 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Iqgap2 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Iqgap2 WT Male (Mean ± SD) | Iqgap2 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.74 ± 1.76 | 24.92 ± 1.72 | 0.0708 |
| Bone Mineral Density (mg/ccm HA) | 1,156.75 ± 10.53 | 1,140.26 ± 9.47 | 0.0082* |
| Cortical Area (mm^2) | 0.792 ± 0.084 | 0.698 ± 0.085 | 0.0573 |
| Cortical Area / Total Area (%) | 41.31 ± 2.11 | 40.14 ± 0.95 | 0.2031 |
| Cortical Mask (dimensionless) | 0.794 ± 0.084 | 0.700 ± 0.086 | 0.0564 |
| Cortical Porosity (%) | 0.34 ± 0.13 | 0.285 ± 0.040 | 0.2806 |
| Cortical Thickness (mm) | 0.174 ± 0.014 | 0.160 ± 0.013 | 0.0691 |
| Endocortical Perimeter (mm) | 3.75 ± 0.21 | 3.60 ± 0.18 | 0.1795 |
| Length (mm) | 15.01 ± 0.28 | 14.83 ± 0.36 | 0.3041 |
| Marrow Area (mm^2) | 1.12 ± 0.13 | 1.04 ± 0.10 | 0.1886 |
| Maximum Distance from Centroid (mm) | 2.00 ± 0.10 | 1.89 ± 0.12 | 0.0752 |
| Maximum Moment of Inertia (mm^4) | 0.271 ± 0.053 | 0.224 ± 0.049 | 0.1081 |
| Minimum Distance from Centroid (mm) | 1.322 ± 0.087 | 1.233 ± 0.083 | 0.0709 |
| Minimum Moment of Inertia (mm^4) | 0.141 ± 0.033 | 0.110 ± 0.026 | 0.0711 |
| Periosteal Perimeter (mm) | 4.97 ± 0.34 | 4.64 ± 0.38 | 0.1077 |
| Polar Moment of Inertia (mm^4) | 0.412 ± 0.086 | 0.334 ± 0.074 | 0.0912 |
| Pore Area (mm^2) | 0.0027 ± 0.0009 | 0.0020 ± 0.0005 | 0.1013 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.269 ± 0.038 | 0.235 ± 0.037 | 0.1150 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.211 ± 0.033 | 0.177 ± 0.030 | 0.0623 |
| Tissue Mineral Density (mg/ccm HA) | 1,219.11 ± 8.48 | 1,204.63 ± 10.25 | 0.0122* |
| Total Area (mm^2) | 1.92 ± 0.20 | 1.74 ± 0.19 | 0.0999 |