Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Hspb2 KO Male
M
12wk
B6N(Cg)-Hspb2<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Hspb2 KO Female
F
12wk
B6N(Cg)-Hspb2<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Hspb2 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Hspb2 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Hspb2 WT Male (Mean ± SD) | Hspb2 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 21.37 ± 2.19 | 21.93 ± 0.50 | 0.5462 |
| Bone Mineral Density (mg/ccm HA) | 1,167.30 ± 9.32 | 1,153.60 ± 7.92 | 0.0103* |
| Cortical Area (mm^2) | 0.657 ± 0.082 | 0.689 ± 0.029 | 0.3452 |
| Cortical Area / Total Area (%) | 40.21 ± 2.12 | 39.25 ± 1.50 | 0.3423 |
| Cortical Mask (dimensionless) | 0.659 ± 0.082 | 0.691 ± 0.030 | 0.3432 |
| Cortical Porosity (%) | 0.240 ± 0.034 | 0.267 ± 0.059 | 0.3014 |
| Cortical Thickness (mm) | 0.156 ± 0.014 | 0.1558 ± 0.0058 | 0.9591 |
| Endocortical Perimeter (mm) | 3.49 ± 0.12 | 3.66 ± 0.11 | 0.0171* |
| Length (mm) | 14.54 ± 0.30 | 14.71 ± 0.13 | 0.1995 |
| Marrow Area (mm^2) | 0.971 ± 0.069 | 1.067 ± 0.064 | 0.0176* |
| Maximum Distance from Centroid (mm) | 1.805 ± 0.071 | 1.932 ± 0.059 | 0.0027* |
| Maximum Moment of Inertia (mm^4) | 0.189 ± 0.039 | 0.226 ± 0.016 | 0.0343* |
| Minimum Distance from Centroid (mm) | 1.228 ± 0.055 | 1.231 ± 0.038 | 0.9144 |
| Minimum Moment of Inertia (mm^4) | 0.102 ± 0.019 | 0.1082 ± 0.0095 | 0.4252 |
| Periosteal Perimeter (mm) | 4.32 ± 0.28 | 4.62 ± 0.13 | 0.0210* |
| Polar Moment of Inertia (mm^4) | 0.290 ± 0.058 | 0.334 ± 0.024 | 0.0868 |
| Pore Area (mm^2) | 0.0016 ± 0.0003 | 0.0019 ± 0.0004 | 0.2404 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.208 ± 0.035 | 0.233 ± 0.011 | 0.0864 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.164 ± 0.025 | 0.176 ± 0.011 | 0.2896 |
| Tissue Mineral Density (mg/ccm HA) | 1,240.94 ± 9.16 | 1,222.90 ± 7.57 | 0.0013* |
| Total Area (mm^2) | 1.63 ± 0.14 | 1.758 ± 0.077 | 0.0556 |