Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Rab43 KO Male
M
12wk
B6N(Cg)-Rab43<tm1.1(KOMP)VlcgJ (C57BL/6NTac)
• KO/KO
Rab43 KO Female
F
12wk
B6N(Cg)-Rab43<tm1.1(KOMP)VlcgJ (C57BL/6NTac)
• KO/KO
Rab43 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Rab43 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Rab43 WT Male (Mean ± SD) | Rab43 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.13 ± 2.44 | 22.59 ± 1.92 | 0.0093* |
| Bone Mineral Density (mg/ccm HA) | 1,153.26 ± 8.54 | 1,135.80 ± 7.75 | 0.0013* |
| Cortical Area (mm^2) | 0.73 ± 0.10 | 0.661 ± 0.049 | 0.1351 |
| Cortical Area / Total Area (%) | 40.82 ± 1.06 | 40.19 ± 2.21 | 0.5070 |
| Cortical Mask (dimensionless) | 0.73 ± 0.10 | 0.663 ± 0.050 | 0.1335 |
| Cortical Porosity (%) | 0.34 ± 0.13 | 0.283 ± 0.050 | 0.2754 |
| Cortical Thickness (mm) | 0.164 ± 0.012 | 0.155 ± 0.012 | 0.2002 |
| Endocortical Perimeter (mm) | 3.63 ± 0.29 | 3.51 ± 0.14 | 0.3347 |
| Length (mm) | 14.80 ± 0.31 | 14.22 ± 0.16 | <0.001* |
| Marrow Area (mm^2) | 1.06 ± 0.17 | 0.983 ± 0.077 | 0.3199 |
| Maximum Distance from Centroid (mm) | 1.94 ± 0.15 | 1.870 ± 0.086 | 0.3235 |
| Maximum Moment of Inertia (mm^4) | 0.238 ± 0.069 | 0.203 ± 0.030 | 0.2284 |
| Minimum Distance from Centroid (mm) | 1.26 ± 0.12 | 1.213 ± 0.050 | 0.3171 |
| Minimum Moment of Inertia (mm^4) | 0.122 ± 0.041 | 0.097 ± 0.012 | 0.1438 |
| Periosteal Perimeter (mm) | 4.70 ± 0.47 | 4.26 ± 0.18 | 0.0372* |
| Polar Moment of Inertia (mm^4) | 0.36 ± 0.11 | 0.300 ± 0.040 | 0.1904 |
| Pore Area (mm^2) | 0.0025 ± 0.0010 | 0.0019 ± 0.0005 | 0.1605 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.242 ± 0.049 | 0.216 ± 0.023 | 0.2167 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.190 ± 0.043 | 0.160 ± 0.015 | 0.1062 |
| Tissue Mineral Density (mg/ccm HA) | 1,218.84 ± 7.97 | 1,200.85 ± 6.67 | <0.001* |
| Total Area (mm^2) | 1.79 ± 0.27 | 1.65 ± 0.10 | 0.2198 |