Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Myo3b KO Male
M
12wk
B6N(Cg)-Myo3b<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Myo3b KO Female
F
12wk
B6N(Cg)-Myo3b<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Myo3b WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Myo3b WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Myo3b WT Male (Mean ± SD) | Myo3b KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.08 ± 1.70 | 25.01 ± 1.65 | 0.2524 |
| Bone Mineral Density (mg/ccm HA) | 1,144.90 ± 6.30 | 1,155.41 ± 8.58 | 0.0205* |
| Cortical Area (mm^2) | 0.740 ± 0.052 | 0.800 ± 0.036 | 0.0246* |
| Cortical Area / Total Area (%) | 41.55 ± 1.95 | 40.16 ± 2.31 | 0.2446 |
| Cortical Mask (dimensionless) | 0.742 ± 0.052 | 0.803 ± 0.036 | 0.0226* |
| Cortical Porosity (%) | 0.258 ± 0.033 | 0.364 ± 0.049 | <0.001* |
| Cortical Thickness (mm) | 0.1654 ± 0.0082 | 0.173 ± 0.010 | 0.1542 |
| Endocortical Perimeter (mm) | 3.61 ± 0.16 | 3.87 ± 0.16 | 0.0116* |
| Length (mm) | 14.79 ± 0.20 | 15.18 ± 0.13 | <0.001* |
| Marrow Area (mm^2) | 1.042 ± 0.096 | 1.19 ± 0.10 | 0.0123* |
| Maximum Distance from Centroid (mm) | 1.971 ± 0.088 | 2.053 ± 0.058 | 0.0601 |
| Maximum Moment of Inertia (mm^4) | 0.246 ± 0.033 | 0.298 ± 0.025 | 0.0049* |
| Minimum Distance from Centroid (mm) | 1.228 ± 0.051 | 1.325 ± 0.040 | 0.0013* |
| Minimum Moment of Inertia (mm^4) | 0.115 ± 0.017 | 0.141 ± 0.012 | 0.0055* |
| Periosteal Perimeter (mm) | 4.67 ± 0.26 | 5.13 ± 0.25 | 0.0043* |
| Polar Moment of Inertia (mm^4) | 0.361 ± 0.050 | 0.439 ± 0.035 | 0.0042* |
| Pore Area (mm^2) | 0.0019 ± 0.0002 | 0.0029 ± 0.0004 | <0.001* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.249 ± 0.023 | 0.290 ± 0.018 | 0.0022* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.187 ± 0.021 | 0.213 ± 0.015 | 0.0182* |
| Tissue Mineral Density (mg/ccm HA) | 1,207.33 ± 8.16 | 1,218.88 ± 7.16 | 0.0138* |
| Total Area (mm^2) | 1.78 ± 0.13 | 2.00 ± 0.11 | 0.0047* |