Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Pacsin2 KO Male
M
12wk
B6N(Cg)-Pacsin2<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Pacsin2 KO Female
F
12wk
B6N(Cg)-Pacsin2<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Pacsin2 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Pacsin2 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Pacsin2 WT Male (Mean ± SD) | Pacsin2 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 27.49 ± 2.14 | 23.41 ± 1.46 | <0.001* |
| Bone Mineral Density (mg/ccm HA) | 1,134.99 ± 7.75 | 1,129.78 ± 5.99 | 0.1809 |
| Cortical Area (mm^2) | 0.680 ± 0.063 | 0.657 ± 0.058 | 0.4785 |
| Cortical Area / Total Area (%) | 38.84 ± 1.31 | 37.41 ± 1.62 | 0.0921 |
| Cortical Mask (dimensionless) | 0.682 ± 0.063 | 0.659 ± 0.058 | 0.4849 |
| Cortical Porosity (%) | 0.248 ± 0.024 | 0.298 ± 0.083 | 0.1489 |
| Cortical Thickness (mm) | 0.155 ± 0.011 | 0.1469 ± 0.0084 | 0.1338 |
| Endocortical Perimeter (mm) | 3.66 ± 0.16 | 3.71 ± 0.22 | 0.6290 |
| Length (mm) | 14.74 ± 0.21 | 14.61 ± 0.20 | 0.2482 |
| Marrow Area (mm^2) | 1.069 ± 0.093 | 1.10 ± 0.13 | 0.6140 |
| Maximum Distance from Centroid (mm) | 1.911 ± 0.089 | 1.92 ± 0.11 | 0.8789 |
| Maximum Moment of Inertia (mm^4) | 0.223 ± 0.039 | 0.217 ± 0.044 | 0.8015 |
| Minimum Distance from Centroid (mm) | 1.237 ± 0.050 | 1.244 ± 0.080 | 0.8476 |
| Minimum Moment of Inertia (mm^4) | 0.109 ± 0.019 | 0.108 ± 0.023 | 0.9442 |
| Periosteal Perimeter (mm) | 4.64 ± 0.31 | 4.62 ± 0.36 | 0.9095 |
| Polar Moment of Inertia (mm^4) | 0.332 ± 0.057 | 0.325 ± 0.067 | 0.8466 |
| Pore Area (mm^2) | 0.0017 ± 0.0002 | 0.0020 ± 0.0006 | 0.2430 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.232 ± 0.031 | 0.225 ± 0.032 | 0.6640 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.175 ± 0.024 | 0.172 ± 0.024 | 0.8169 |
| Tissue Mineral Density (mg/ccm HA) | 1,198.45 ± 8.55 | 1,195.07 ± 7.36 | 0.4417 |
| Total Area (mm^2) | 1.75 ± 0.15 | 1.76 ± 0.18 | 0.9306 |