Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Tbc1d4 KO Male
M
12wk
B6N(Cg)-Tbc1d4(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Tbc1d4 KO Female
F
12wk
B6N(Cg)-Tbc1d4(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Tbc1d4 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Tbc1d4 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Tbc1d4 WT Male (Mean ± SD) | Tbc1d4 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.12 ± 1.68 | 25.80 ± 1.77 | 0.7369 |
| Bone Mineral Density (mg/ccm HA) | 1,144.45 ± 7.17 | 1,156.17 ± 7.22 | 0.0087* |
| Cortical Area (mm^2) | 0.736 ± 0.057 | 0.744 ± 0.065 | 0.8009 |
| Cortical Area / Total Area (%) | 41.14 ± 2.19 | 40.71 ± 0.93 | 0.6437 |
| Cortical Mask (dimensionless) | 0.738 ± 0.057 | 0.746 ± 0.066 | 0.7932 |
| Cortical Porosity (%) | 0.250 ± 0.034 | 0.293 ± 0.070 | 0.1694 |
| Cortical Thickness (mm) | 0.1635 ± 0.0099 | 0.1677 ± 0.0080 | 0.3917 |
| Endocortical Perimeter (mm) | 3.63 ± 0.16 | 3.68 ± 0.14 | 0.5426 |
| Length (mm) | 14.79 ± 0.20 | 14.81 ± 0.21 | 0.8453 |
| Marrow Area (mm^2) | 1.052 ± 0.091 | 1.080 ± 0.078 | 0.5463 |
| Maximum Distance from Centroid (mm) | 1.966 ± 0.091 | 1.97 ± 0.11 | 0.9457 |
| Maximum Moment of Inertia (mm^4) | 0.245 ± 0.035 | 0.252 ± 0.044 | 0.7336 |
| Minimum Distance from Centroid (mm) | 1.233 ± 0.046 | 1.273 ± 0.031 | 0.0791 |
| Minimum Moment of Inertia (mm^4) | 0.116 ± 0.016 | 0.122 ± 0.017 | 0.5164 |
| Periosteal Perimeter (mm) | 4.67 ± 0.25 | 4.75 ± 0.27 | 0.5979 |
| Polar Moment of Inertia (mm^4) | 0.361 ± 0.050 | 0.374 ± 0.060 | 0.6602 |
| Pore Area (mm^2) | 0.0018 ± 0.0002 | 0.0022 ± 0.0006 | 0.1597 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.248 ± 0.024 | 0.254 ± 0.033 | 0.6938 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.187 ± 0.020 | 0.191 ± 0.022 | 0.7689 |
| Tissue Mineral Density (mg/ccm HA) | 1,207.42 ± 8.01 | 1,221.23 ± 6.98 | 0.0040* |
| Total Area (mm^2) | 1.79 ± 0.13 | 1.83 ± 0.14 | 0.6127 |