Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Lrch1 KO Male
M
12wk
B6N(Cg)-Lrch1<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Lrch1 KO Female
F
12wk
B6N(Cg)-Lrch1<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Lrch1 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Lrch1 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Lrch1 WT Male (Mean ± SD) | Lrch1 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 25.21 ± 1.36 | 26.79 ± 2.85 | 0.2297 |
| Bone Mineral Density (mg/ccm HA) | 1,141.76 ± 5.88 | 1,143.91 ± 10.34 | 0.6569 |
| Cortical Area (mm^2) | 0.733 ± 0.075 | 0.772 ± 0.043 | 0.3131 |
| Cortical Area / Total Area (%) | 40.84 ± 1.10 | 38.09 ± 2.69 | 0.0327* |
| Cortical Mask (dimensionless) | 0.735 ± 0.075 | 0.774 ± 0.044 | 0.3156 |
| Cortical Porosity (%) | 0.267 ± 0.031 | 0.253 ± 0.041 | 0.5279 |
| Cortical Thickness (mm) | 0.164 ± 0.010 | 0.162 ± 0.010 | 0.7178 |
| Endocortical Perimeter (mm) | 3.65 ± 0.20 | 3.97 ± 0.21 | 0.0182* |
| Length (mm) | 14.75 ± 0.29 | 14.85 ± 0.19 | 0.5057 |
| Marrow Area (mm^2) | 1.06 ± 0.12 | 1.26 ± 0.13 | 0.0167* |
| Maximum Distance from Centroid (mm) | 1.94 ± 0.12 | 2.07 ± 0.13 | 0.0975 |
| Maximum Moment of Inertia (mm^4) | 0.242 ± 0.048 | 0.287 ± 0.039 | 0.1054 |
| Minimum Distance from Centroid (mm) | 1.249 ± 0.079 | 1.341 ± 0.051 | 0.0384* |
| Minimum Moment of Inertia (mm^4) | 0.119 ± 0.025 | 0.145 ± 0.015 | 0.0594 |
| Periosteal Perimeter (mm) | 4.68 ± 0.38 | 5.04 ± 0.29 | 0.0925 |
| Polar Moment of Inertia (mm^4) | 0.361 ± 0.073 | 0.432 ± 0.053 | 0.0845 |
| Pore Area (mm^2) | 0.0020 ± 0.0004 | 0.0020 ± 0.0004 | 0.9763 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.247 ± 0.035 | 0.276 ± 0.022 | 0.1218 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.189 ± 0.028 | 0.216 ± 0.015 | 0.0759 |
| Tissue Mineral Density (mg/ccm HA) | 1,202.34 ± 6.26 | 1,206.81 ± 10.18 | 0.3668 |
| Total Area (mm^2) | 1.80 ± 0.19 | 2.03 ± 0.15 | 0.0349* |