Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Cbln3 KO Male
M
12wk
B6N(Cg)-Cbln3 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Cbln3 KO Female
F
12wk
B6N(Cg)-Cbln3 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Cbln3 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Cbln3 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Cbln3 WT Male (Mean ± SD) | Cbln3 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 25.96 ± 1.60 | 29.62 ± 2.20 | 0.0032* |
| Bone Mineral Density (mg/ccm HA) | 1,115.44 ± 4.71 | 1,099.49 ± 10.46 | 0.0025* |
| Cortical Area (mm^2) | 0.691 ± 0.027 | 0.734 ± 0.039 | 0.0306* |
| Cortical Area / Total Area (%) | 40.24 ± 0.80 | 40.36 ± 1.28 | 0.8382 |
| Cortical Mask (dimensionless) | 0.693 ± 0.027 | 0.738 ± 0.037 | 0.0230* |
| Cortical Porosity (%) | 0.323 ± 0.084 | 0.52 ± 0.33 | 0.1444 |
| Cortical Thickness (mm) | 0.1564 ± 0.0044 | 0.1638 ± 0.0074 | 0.0413* |
| Endocortical Perimeter (mm) | 3.587 ± 0.074 | 3.684 ± 0.068 | 0.0231* |
| Length (mm) | 14.55 ± 0.19 | 14.70 ± 0.15 | 0.1202 |
| Marrow Area (mm^2) | 1.024 ± 0.042 | 1.080 ± 0.040 | 0.0229* |
| Maximum Distance from Centroid (mm) | 1.925 ± 0.056 | 2.034 ± 0.080 | 0.0102* |
| Maximum Moment of Inertia (mm^4) | 0.224 ± 0.021 | 0.254 ± 0.029 | 0.0434* |
| Minimum Distance from Centroid (mm) | 1.200 ± 0.023 | 1.232 ± 0.020 | 0.0150* |
| Minimum Moment of Inertia (mm^4) | 0.1034 ± 0.0059 | 0.1155 ± 0.0061 | 0.0021* |
| Periosteal Perimeter (mm) | 4.68 ± 0.11 | 4.862 ± 0.100 | 0.0061* |
| Polar Moment of Inertia (mm^4) | 0.327 ± 0.026 | 0.369 ± 0.033 | 0.0194* |
| Pore Area (mm^2) | 0.0023 ± 0.0007 | 0.0037 ± 0.0020 | 0.0858 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.232 ± 0.016 | 0.249 ± 0.020 | 0.1024 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.1723 ± 0.0076 | 0.1874 ± 0.0085 | 0.0034* |
| Tissue Mineral Density (mg/ccm HA) | 1,184.55 ± 5.78 | 1,164.58 ± 8.03 | <0.001* |
| Total Area (mm^2) | 1.718 ± 0.063 | 1.818 ± 0.065 | 0.0107* |