Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Kcnh3 KO Male
M
12wk
B6N(Cg)-Kcnh3tm1.1(KOMP)Vlcg/2J (C57BL/6NTac)
• KO/KO
Kcnh3 KO Female
F
12wk
B6N(Cg)-Kcnh3tm1.1(KOMP)Vlcg/2J (C57BL/6NTac)
• KO/KO
Kcnh3 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Kcnh3 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Kcnh3 WT Male (Mean ± SD) | Kcnh3 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 23.90 ± 1.25 | 26.21 ± 2.03 | 0.0224* |
| Bone Mineral Density (mg/ccm HA) | 1,131.29 ± 4.88 | 1,109.01 ± 6.19 | <0.001* |
| Cortical Area (mm^2) | 0.668 ± 0.040 | 0.691 ± 0.023 | 0.2054 |
| Cortical Area / Total Area (%) | 41.12 ± 1.23 | 38.81 ± 1.55 | 0.0080* |
| Cortical Mask (dimensionless) | 0.670 ± 0.041 | 0.694 ± 0.024 | 0.1870 |
| Cortical Porosity (%) | 0.334 ± 0.055 | 0.51 ± 0.11 | 0.0017* |
| Cortical Thickness (mm) | 0.1568 ± 0.0071 | 0.1534 ± 0.0051 | 0.3162 |
| Endocortical Perimeter (mm) | 3.459 ± 0.061 | 3.695 ± 0.095 | <0.001* |
| Length (mm) | 14.35 ± 0.17 | 14.68 ± 0.20 | 0.0060* |
| Marrow Area (mm^2) | 0.953 ± 0.033 | 1.087 ± 0.056 | <0.001* |
| Maximum Distance from Centroid (mm) | 1.875 ± 0.065 | 1.962 ± 0.037 | 0.0079* |
| Maximum Moment of Inertia (mm^4) | 0.201 ± 0.019 | 0.231 ± 0.014 | 0.0044* |
| Minimum Distance from Centroid (mm) | 1.188 ± 0.022 | 1.222 ± 0.016 | 0.0054* |
| Minimum Moment of Inertia (mm^4) | 0.0946 ± 0.0083 | 0.1081 ± 0.0055 | 0.0031* |
| Periosteal Perimeter (mm) | 4.51 ± 0.10 | 4.65 ± 0.13 | 0.0443* |
| Polar Moment of Inertia (mm^4) | 0.296 ± 0.027 | 0.340 ± 0.018 | 0.0032* |
| Pore Area (mm^2) | 0.0023 ± 0.0004 | 0.0036 ± 0.0009 | 0.0028* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.214 ± 0.014 | 0.236 ± 0.012 | 0.0084* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.159 ± 0.012 | 0.1768 ± 0.0073 | 0.0041* |
| Tissue Mineral Density (mg/ccm HA) | 1,205.54 ± 5.10 | 1,184.53 ± 6.53 | <0.001* |
| Total Area (mm^2) | 1.622 ± 0.065 | 1.781 ± 0.056 | <0.001* |