Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Tpcn1 KO Male
M
12wk
B6N(Cg)-Tpcn1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Tpcn1 KO Female
F
12wk
B6N(Cg)-Tpcn1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Tpcn1 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Tpcn1 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Tpcn1 WT Male (Mean ± SD) | Tpcn1 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.39 ± 2.97 | 24.99 ± 2.84 | 0.7046 |
| Bone Mineral Density (mg/ccm HA) | 1,144.64 ± 6.35 | 1,167.13 ± 9.19 | <0.001* |
| Cortical Area (mm^2) | 0.661 ± 0.069 | 0.70 ± 0.10 | 0.4075 |
| Cortical Area / Total Area (%) | 41.35 ± 2.36 | 41.17 ± 1.90 | 0.8775 |
| Cortical Mask (dimensionless) | 0.663 ± 0.070 | 0.70 ± 0.10 | 0.4112 |
| Cortical Porosity (%) | 0.253 ± 0.025 | 0.213 ± 0.048 | 0.0720 |
| Cortical Thickness (mm) | 0.1585 ± 0.0079 | 0.162 ± 0.016 | 0.6231 |
| Endocortical Perimeter (mm) | 3.43 ± 0.28 | 3.53 ± 0.16 | 0.4411 |
| Length (mm) | 14.59 ± 0.32 | 14.44 ± 0.38 | 0.4522 |
| Marrow Area (mm^2) | 0.94 ± 0.16 | 0.995 ± 0.093 | 0.4784 |
| Maximum Distance from Centroid (mm) | 1.82 ± 0.16 | 1.917 ± 0.099 | 0.2026 |
| Maximum Moment of Inertia (mm^4) | 0.196 ± 0.055 | 0.229 ± 0.060 | 0.2941 |
| Minimum Distance from Centroid (mm) | 1.202 ± 0.058 | 1.185 ± 0.064 | 0.6111 |
| Minimum Moment of Inertia (mm^4) | 0.097 ± 0.023 | 0.103 ± 0.025 | 0.6166 |
| Periosteal Perimeter (mm) | 4.34 ± 0.48 | 4.44 ± 0.36 | 0.6500 |
| Polar Moment of Inertia (mm^4) | 0.292 ± 0.078 | 0.332 ± 0.085 | 0.3708 |
| Pore Area (mm^2) | 0.0017 ± 0.0003 | 0.0015 ± 0.0005 | 0.4179 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.212 ± 0.039 | 0.237 ± 0.049 | 0.3076 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.159 ± 0.029 | 0.172 ± 0.032 | 0.4335 |
| Tissue Mineral Density (mg/ccm HA) | 1,210.07 ± 6.88 | 1,233.78 ± 7.30 | <0.001* |
| Total Area (mm^2) | 1.61 ± 0.22 | 1.70 ± 0.19 | 0.4263 |