Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Myo7b KO Male
M
12wk
B6N(Cg)-Myo7b<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Myo7b KO Female
F
12wk
B6N(Cg)-Myo7b<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Myo7b WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Myo7b WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Myo7b WT Male (Mean ± SD) | Myo7b KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Bone Mineral Density (mg/ccm HA) | 1,162.20 ± 7.10 | 1,152.22 ± 7.81 | 0.0253* |
| Cortical Area (mm^2) | 0.641 ± 0.049 | 0.669 ± 0.098 | 0.5220 |
| Cortical Area / Total Area (%) | 38.69 ± 1.39 | 38.99 ± 1.35 | 0.6864 |
| Cortical Mask (dimensionless) | 0.643 ± 0.049 | 0.670 ± 0.098 | 0.5176 |
| Cortical Porosity (%) | 0.210 ± 0.032 | 0.259 ± 0.044 | 0.0312* |
| Cortical Thickness (mm) | 0.1494 ± 0.0092 | 0.153 ± 0.014 | 0.5646 |
| Endocortical Perimeter (mm) | 3.569 ± 0.096 | 3.61 ± 0.25 | 0.6686 |
| Length (mm) | 14.42 ± 0.16 | 14.56 ± 0.44 | 0.4442 |
| Marrow Area (mm^2) | 1.014 ± 0.055 | 1.04 ± 0.14 | 0.6127 |
| Maximum Distance from Centroid (mm) | 1.870 ± 0.067 | 1.91 ± 0.14 | 0.5325 |
| Maximum Moment of Inertia (mm^4) | 0.194 ± 0.027 | 0.214 ± 0.058 | 0.4069 |
| Minimum Distance from Centroid (mm) | 1.226 ± 0.039 | 1.245 ± 0.096 | 0.6352 |
| Minimum Moment of Inertia (mm^4) | 0.099 ± 0.012 | 0.106 ± 0.028 | 0.5277 |
| Periosteal Perimeter (mm) | 4.36 ± 0.15 | 4.51 ± 0.49 | 0.4536 |
| Polar Moment of Inertia (mm^4) | 0.292 ± 0.038 | 0.321 ± 0.086 | 0.4412 |
| Pore Area (mm^2) | 0.0014 ± 0.0003 | 0.0018 ± 0.0005 | 0.0753 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.206 ± 0.021 | 0.221 ± 0.046 | 0.4451 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.161 ± 0.015 | 0.168 ± 0.033 | 0.5878 |
| Tissue Mineral Density (mg/ccm HA) | 1,237.11 ± 7.41 | 1,222.78 ± 6.33 | 0.0016* |
| Total Area (mm^2) | 1.657 ± 0.095 | 1.71 ± 0.23 | 0.5593 |