Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Cyb5d2 KO Male
M
12wk
B6N(Cg)-Cyb5d2<tm1.1(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Cyb5d2 KO Female
F
12wk
B6N(Cg)-Cyb5d2<tm1.1(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Cyb5d2 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Cyb5d2 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Cyb5d2 WT Male (Mean ± SD) | Cyb5d2 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.07 ± 1.17 | 26.04 ± 1.56 | 0.9682 |
| Bone Mineral Density (mg/ccm HA) | 1,160.31 ± 10.68 | 1,146.54 ± 6.97 | 0.0127* |
| Cortical Area (mm^2) | 0.723 ± 0.048 | 0.784 ± 0.036 | 0.0186* |
| Cortical Area / Total Area (%) | 42.04 ± 2.28 | 39.59 ± 2.25 | 0.0628 |
| Cortical Mask (dimensionless) | 0.725 ± 0.048 | 0.787 ± 0.037 | 0.0176* |
| Cortical Porosity (%) | 0.268 ± 0.023 | 0.39 ± 0.14 | 0.0502 |
| Cortical Thickness (mm) | 0.165 ± 0.011 | 0.1680 ± 0.0070 | 0.5162 |
| Endocortical Perimeter (mm) | 3.534 ± 0.078 | 3.88 ± 0.23 | 0.0052* |
| Length (mm) | 14.76 ± 0.12 | 14.90 ± 0.17 | 0.1243 |
| Marrow Area (mm^2) | 0.994 ± 0.044 | 1.20 ± 0.14 | 0.0063* |
| Maximum Distance from Centroid (mm) | 1.909 ± 0.058 | 2.062 ± 0.076 | <0.001* |
| Maximum Moment of Inertia (mm^4) | 0.223 ± 0.017 | 0.291 ± 0.035 | <0.001* |
| Minimum Distance from Centroid (mm) | 1.221 ± 0.027 | 1.332 ± 0.086 | 0.0110* |
| Minimum Moment of Inertia (mm^4) | 0.1109 ± 0.0093 | 0.139 ± 0.021 | 0.0094* |
| Periosteal Perimeter (mm) | 4.549 ± 0.090 | 5.02 ± 0.28 | 0.0025* |
| Polar Moment of Inertia (mm^4) | 0.334 ± 0.025 | 0.430 ± 0.055 | 0.0020* |
| Pore Area (mm^2) | 0.0019 ± 0.0002 | 0.0031 ± 0.0012 | 0.0321* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.234 ± 0.013 | 0.282 ± 0.024 | <0.001* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.182 ± 0.012 | 0.208 ± 0.019 | 0.0071* |
| Tissue Mineral Density (mg/ccm HA) | 1,225.85 ± 8.99 | 1,209.14 ± 6.86 | 0.0016* |
| Total Area (mm^2) | 1.719 ± 0.050 | 1.99 ± 0.17 | 0.0038* |