Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Pkn3 KO Male
M
12wk
B6N(Cg)-Pkn3<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Pkn3 KO Female
F
12wk
B6N(Cg)-Pkn3<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Pkn3 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Pkn3 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Pkn3 WT Male (Mean ± SD) | Pkn3 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.54 ± 1.19 | 23.44 ± 2.49 | 0.3400 |
| Bone Mineral Density (mg/ccm HA) | 1,130.64 ± 7.19 | 1,152.57 ± 3.60 | <0.001* |
| Cortical Area (mm^2) | 0.634 ± 0.033 | 0.742 ± 0.077 | 0.0044* |
| Cortical Area / Total Area (%) | 38.47 ± 1.20 | 41.85 ± 1.04 | <0.001* |
| Cortical Mask (dimensionless) | 0.636 ± 0.033 | 0.744 ± 0.077 | 0.0043* |
| Cortical Porosity (%) | 0.271 ± 0.032 | 0.301 ± 0.057 | 0.2392 |
| Cortical Thickness (mm) | 0.1471 ± 0.0054 | 0.169 ± 0.011 | <0.001* |
| Endocortical Perimeter (mm) | 3.566 ± 0.072 | 3.59 ± 0.14 | 0.7168 |
| Length (mm) | 12.71 ± 4.81 | 14.62 ± 0.13 | 0.3115 |
| Marrow Area (mm^2) | 1.013 ± 0.041 | 1.026 ± 0.080 | 0.6948 |
| Maximum Distance from Centroid (mm) | 1.848 ± 0.048 | 1.917 ± 0.095 | 0.1154 |
| Maximum Moment of Inertia (mm^4) | 0.190 ± 0.016 | 0.239 ± 0.046 | 0.0257* |
| Minimum Distance from Centroid (mm) | 1.209 ± 0.026 | 1.245 ± 0.065 | 0.2134 |
| Minimum Moment of Inertia (mm^4) | 0.0968 ± 0.0086 | 0.117 ± 0.022 | 0.0355* |
| Periosteal Perimeter (mm) | 4.40 ± 0.13 | 4.57 ± 0.25 | 0.1241 |
| Polar Moment of Inertia (mm^4) | 0.287 ± 0.023 | 0.357 ± 0.067 | 0.0210* |
| Pore Area (mm^2) | 0.0017 ± 0.0002 | 0.0022 ± 0.0005 | 0.0191* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.205 ± 0.013 | 0.248 ± 0.036 | 0.0173* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.160 ± 0.012 | 0.187 ± 0.025 | 0.0188* |
| Tissue Mineral Density (mg/ccm HA) | 1,198.63 ± 8.01 | 1,215.63 ± 4.59 | <0.001* |
| Total Area (mm^2) | 1.648 ± 0.062 | 1.77 ± 0.15 | 0.0735 |