Skeletal Phenotyping of Ifnl3 Knockout Mice

ROSSA-20260926-6430

Back to Search
Study Datasets
Microcomputed Tomography (µCT) 1 uploads
Bone: Femur Region: Cortical
Microcomputed Tomography (µCT) 1 uploads
Bone: Femur Region: Trabecular
Microcomputed Tomography (µCT) 1 uploads
Bone: Vertebra Region: Trabecular
Sample Groups
Ifnl3 KO Male M 12wk
B6N(Cg)-Infl3<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac) • KO/KO
Ifnl3 KO Female F 12wk
B6N(Cg)-Infl3<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac) • KO/KO
Ifnl3 WT Male Control M 12wk
C57BL/6NTac (C57BL/6NTac) • +/+
Ifnl3 WT Female Control F 12wk
C57BL/6NTac (C57BL/6NTac) • +/+

Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical

Download CSV
Variable Ifnl3 WT Male (Mean ± SD) Ifnl3 KO Male (Mean ± SD) T-test (p-Value)
Body Weight (g) 26.07 ± 1.17 24.33 ± 1.65 0.0546
Bone Mineral Density (mg/ccm HA) 1,160.31 ± 10.68 1,144.34 ± 9.32 0.0191*
Cortical Area (mm^2) 0.723 ± 0.048 0.659 ± 0.035 0.0250*
Cortical Area / Total Area (%) 42.04 ± 2.28 40.19 ± 1.80 0.1544
Cortical Mask (dimensionless) 0.725 ± 0.048 0.660 ± 0.035 0.0250*
Cortical Porosity (%) 0.268 ± 0.023 0.263 ± 0.032 0.7508
Cortical Thickness (mm) 0.165 ± 0.011 0.1532 ± 0.0087 0.0816
Endocortical Perimeter (mm) 3.534 ± 0.078 3.506 ± 0.062 0.5168
Length (mm) 14.76 ± 0.12 14.54 ± 0.14 0.0136*
Marrow Area (mm^2) 0.994 ± 0.044 0.978 ± 0.034 0.5110
Maximum Distance from Centroid (mm) 1.909 ± 0.058 1.848 ± 0.065 0.1118
Maximum Moment of Inertia (mm^4) 0.223 ± 0.017 0.198 ± 0.018 0.0265*
Minimum Distance from Centroid (mm) 1.221 ± 0.027 1.186 ± 0.034 0.0707
Minimum Moment of Inertia (mm^4) 0.1109 ± 0.0093 0.0969 ± 0.0047 0.0088*
Periosteal Perimeter (mm) 4.549 ± 0.090 4.41 ± 0.12 0.0363*
Polar Moment of Inertia (mm^4) 0.334 ± 0.025 0.295 ± 0.020 0.0127*
Pore Area (mm^2) 0.0019 ± 0.0002 0.0017 ± 0.0003 0.1984
Section Modulus about Maximum Moment of Inertia (mm^3) 0.234 ± 0.013 0.214 ± 0.014 0.0215*
Section Modulus about Minimum Moment of Inertia (mm^3) 0.182 ± 0.012 0.1636 ± 0.0090 0.0135*
Tissue Mineral Density (mg/ccm HA) 1,225.85 ± 8.99 1,212.68 ± 9.53 0.0307*
Total Area (mm^2) 1.719 ± 0.050 1.639 ± 0.038 0.0104*