Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Hspb1 KO Male
M
12wk
B6N(Cg)-Hspb1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Hspb1 KO Female
F
12wk
B6N(Cg)-Hspb1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Hspb1 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Hspb1 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Hspb1 WT Male (Mean ± SD) | Hspb1 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.74 ± 1.76 | 24.98 ± 1.04 | 0.0395* |
| Bone Mineral Density (mg/ccm HA) | 1,156.75 ± 10.53 | 1,164.14 ± 9.42 | 0.1878 |
| Cortical Area (mm^2) | 0.792 ± 0.084 | 0.797 ± 0.061 | 0.8872 |
| Cortical Area / Total Area (%) | 41.31 ± 2.11 | 42.73 ± 0.71 | 0.1139 |
| Cortical Mask (dimensionless) | 0.794 ± 0.084 | 0.800 ± 0.062 | 0.8921 |
| Cortical Porosity (%) | 0.34 ± 0.13 | 0.304 ± 0.047 | 0.4767 |
| Cortical Thickness (mm) | 0.174 ± 0.014 | 0.177 ± 0.011 | 0.5909 |
| Endocortical Perimeter (mm) | 3.75 ± 0.21 | 3.66 ± 0.12 | 0.3232 |
| Length (mm) | 15.01 ± 0.28 | 15.00 ± 0.21 | 0.9018 |
| Marrow Area (mm^2) | 1.12 ± 0.13 | 1.065 ± 0.071 | 0.3227 |
| Maximum Distance from Centroid (mm) | 2.00 ± 0.10 | 2.008 ± 0.089 | 0.9303 |
| Maximum Moment of Inertia (mm^4) | 0.271 ± 0.053 | 0.273 ± 0.040 | 0.9489 |
| Minimum Distance from Centroid (mm) | 1.322 ± 0.087 | 1.264 ± 0.052 | 0.1543 |
| Minimum Moment of Inertia (mm^4) | 0.141 ± 0.033 | 0.130 ± 0.018 | 0.4369 |
| Periosteal Perimeter (mm) | 4.97 ± 0.34 | 4.86 ± 0.26 | 0.5053 |
| Polar Moment of Inertia (mm^4) | 0.412 ± 0.086 | 0.402 ± 0.057 | 0.8093 |
| Pore Area (mm^2) | 0.0027 ± 0.0009 | 0.0025 ± 0.0005 | 0.5557 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.269 ± 0.038 | 0.271 ± 0.030 | 0.9371 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.211 ± 0.033 | 0.204 ± 0.021 | 0.6599 |
| Tissue Mineral Density (mg/ccm HA) | 1,219.11 ± 8.48 | 1,225.61 ± 12.26 | 0.2682 |
| Total Area (mm^2) | 1.92 ± 0.20 | 1.87 ± 0.13 | 0.5674 |