Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Stk16 KO Male
M
12wk
B6N(Cg)-Stk16 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Stk16 KO Female
F
12wk
B6N(Cg)-Stk16 tm1.1(KOMP)Vlcg/J (C57BL/6NTac)
• KO/KO
Stk16 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Stk16 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Stk16 WT Male (Mean ± SD) | Stk16 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 20.98 ± 2.15 | 24.78 ± 1.81 | 0.0030* |
| Bone Mineral Density (mg/ccm HA) | 1,175.21 ± 7.08 | 1,143.15 ± 12.22 | <0.001* |
| Cortical Area (mm^2) | 0.689 ± 0.050 | 0.684 ± 0.083 | 0.9071 |
| Cortical Area / Total Area (%) | 41.13 ± 1.63 | 38.93 ± 2.94 | 0.1057 |
| Cortical Mask (dimensionless) | 0.691 ± 0.050 | 0.687 ± 0.083 | 0.9174 |
| Cortical Porosity (%) | 0.278 ± 0.028 | 0.343 ± 0.052 | 0.0114* |
| Cortical Thickness (mm) | 0.162 ± 0.010 | 0.156 ± 0.019 | 0.5223 |
| Endocortical Perimeter (mm) | 3.52 ± 0.14 | 3.66 ± 0.17 | 0.0979 |
| Length (mm) | 14.18 ± 0.46 | 14.57 ± 0.30 | 0.0839 |
| Marrow Area (mm^2) | 0.985 ± 0.078 | 1.070 ± 0.100 | 0.0988 |
| Maximum Distance from Centroid (mm) | 1.809 ± 0.076 | 1.91 ± 0.10 | 0.0614 |
| Maximum Moment of Inertia (mm^4) | 0.199 ± 0.026 | 0.219 ± 0.041 | 0.2906 |
| Minimum Distance from Centroid (mm) | 1.268 ± 0.047 | 1.254 ± 0.055 | 0.6117 |
| Minimum Moment of Inertia (mm^4) | 0.110 ± 0.015 | 0.111 ± 0.021 | 0.9096 |
| Periosteal Perimeter (mm) | 4.27 ± 0.27 | 4.57 ± 0.34 | 0.0935 |
| Polar Moment of Inertia (mm^4) | 0.309 ± 0.040 | 0.331 ± 0.062 | 0.4530 |
| Pore Area (mm^2) | 0.0019 ± 0.0002 | 0.0024 ± 0.0006 | 0.0777 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.219 ± 0.022 | 0.229 ± 0.034 | 0.5413 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.173 ± 0.018 | 0.177 ± 0.026 | 0.7889 |
| Tissue Mineral Density (mg/ccm HA) | 1,246.93 ± 8.00 | 1,206.92 ± 16.14 | <0.001* |
| Total Area (mm^2) | 1.68 ± 0.12 | 1.76 ± 0.15 | 0.2811 |