Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Pnmt KO Male
M
12wk
B6N(Cg)-Pnmt<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Pnmt KO Female
F
12wk
B6N(Cg)-Pnmt<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Pnmt WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Pnmt WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Pnmt WT Male (Mean ± SD) | Pnmt KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 22.43 ± 0.65 | 21.39 ± 0.84 | 0.0215* |
| Bone Mineral Density (mg/ccm HA) | 1,170.29 ± 7.53 | 1,155.18 ± 3.83 | <0.001* |
| Cortical Area (mm^2) | 0.673 ± 0.059 | 0.654 ± 0.061 | 0.5663 |
| Cortical Area / Total Area (%) | 40.83 ± 1.56 | 40.27 ± 1.83 | 0.5458 |
| Cortical Mask (dimensionless) | 0.674 ± 0.059 | 0.656 ± 0.062 | 0.5718 |
| Cortical Porosity (%) | 0.234 ± 0.037 | 0.266 ± 0.049 | 0.1835 |
| Cortical Thickness (mm) | 0.1586 ± 0.0096 | 0.155 ± 0.012 | 0.5268 |
| Endocortical Perimeter (mm) | 3.49 ± 0.14 | 3.483 ± 0.099 | 0.8675 |
| Length (mm) | 14.70 ± 0.16 | 14.55 ± 0.19 | 0.1294 |
| Marrow Area (mm^2) | 0.973 ± 0.076 | 0.966 ± 0.054 | 0.8523 |
| Maximum Distance from Centroid (mm) | 1.801 ± 0.077 | 1.819 ± 0.082 | 0.6736 |
| Maximum Moment of Inertia (mm^4) | 0.194 ± 0.032 | 0.189 ± 0.032 | 0.7999 |
| Minimum Distance from Centroid (mm) | 1.239 ± 0.040 | 1.213 ± 0.033 | 0.1989 |
| Minimum Moment of Inertia (mm^4) | 0.104 ± 0.016 | 0.099 ± 0.012 | 0.4553 |
| Periosteal Perimeter (mm) | 4.39 ± 0.19 | 4.34 ± 0.18 | 0.5830 |
| Polar Moment of Inertia (mm^4) | 0.298 ± 0.048 | 0.288 ± 0.044 | 0.6822 |
| Pore Area (mm^2) | 0.0016 ± 0.0003 | 0.0018 ± 0.0004 | 0.4334 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.214 ± 0.027 | 0.207 ± 0.026 | 0.6165 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.168 ± 0.020 | 0.162 ± 0.016 | 0.5674 |
| Tissue Mineral Density (mg/ccm HA) | 1,242.21 ± 9.23 | 1,226.76 ± 8.27 | 0.0053* |
| Total Area (mm^2) | 1.65 ± 0.13 | 1.62 ± 0.10 | 0.6836 |