Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Sfxn4 KO Male
M
12wk
B6N(Cg)-Sfxn4<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Sfxn4 KO Female
F
12wk
B6N(Cg)-Sfxn4<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Sfxn4 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Sfxn4 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Sfxn4 WT Male (Mean ± SD) | Sfxn4 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.54 ± 1.19 | 23.07 ± 1.47 | 0.0815 |
| Bone Mineral Density (mg/ccm HA) | 1,130.64 ± 7.19 | 1,147.86 ± 7.75 | <0.001* |
| Cortical Area (mm^2) | 0.634 ± 0.033 | 0.697 ± 0.070 | 0.0522 |
| Cortical Area / Total Area (%) | 38.47 ± 1.20 | 40.36 ± 1.82 | 0.0371* |
| Cortical Mask (dimensionless) | 0.636 ± 0.033 | 0.699 ± 0.071 | 0.0527 |
| Cortical Porosity (%) | 0.271 ± 0.032 | 0.28 ± 0.12 | 0.8261 |
| Cortical Thickness (mm) | 0.1471 ± 0.0054 | 0.159 ± 0.012 | 0.0418* |
| Endocortical Perimeter (mm) | 3.566 ± 0.072 | 3.59 ± 0.15 | 0.7361 |
| Length (mm) | 12.71 ± 4.81 | 14.56 ± 0.27 | 0.3270 |
| Marrow Area (mm^2) | 1.013 ± 0.041 | 1.026 ± 0.089 | 0.7156 |
| Maximum Distance from Centroid (mm) | 1.848 ± 0.048 | 1.875 ± 0.078 | 0.4492 |
| Maximum Moment of Inertia (mm^4) | 0.190 ± 0.016 | 0.215 ± 0.039 | 0.1330 |
| Minimum Distance from Centroid (mm) | 1.209 ± 0.026 | 1.245 ± 0.062 | 0.1759 |
| Minimum Moment of Inertia (mm^4) | 0.0968 ± 0.0086 | 0.111 ± 0.021 | 0.1063 |
| Periosteal Perimeter (mm) | 4.40 ± 0.13 | 4.47 ± 0.28 | 0.5133 |
| Polar Moment of Inertia (mm^4) | 0.287 ± 0.023 | 0.327 ± 0.060 | 0.1205 |
| Pore Area (mm^2) | 0.0017 ± 0.0002 | 0.0020 ± 0.0010 | 0.4558 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.205 ± 0.013 | 0.229 ± 0.033 | 0.0989 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.160 ± 0.012 | 0.178 ± 0.024 | 0.0936 |
| Tissue Mineral Density (mg/ccm HA) | 1,198.63 ± 8.01 | 1,213.26 ± 5.91 | 0.0016* |
| Total Area (mm^2) | 1.648 ± 0.062 | 1.72 ± 0.15 | 0.2264 |