Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Pcsk4 KO Male
M
12wk
B6N(Cg)-Pcsk4<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Pcsk4 KO Female
F
12wk
B6N(Cg)-Pcsk4<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Pcsk4 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Pcsk4 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Pcsk4 WT Male (Mean ± SD) | Pcsk4 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.74 ± 1.76 | 26.31 ± 2.84 | 0.7393 |
| Bone Mineral Density (mg/ccm HA) | 1,156.75 ± 10.53 | 1,152.48 ± 5.75 | 0.3621 |
| Cortical Area (mm^2) | 0.792 ± 0.084 | 0.75 ± 0.11 | 0.4235 |
| Cortical Area / Total Area (%) | 41.31 ± 2.11 | 40.18 ± 1.53 | 0.2729 |
| Cortical Mask (dimensionless) | 0.794 ± 0.084 | 0.75 ± 0.11 | 0.4168 |
| Cortical Porosity (%) | 0.34 ± 0.13 | 0.261 ± 0.021 | 0.1198 |
| Cortical Thickness (mm) | 0.174 ± 0.014 | 0.164 ± 0.015 | 0.2091 |
| Endocortical Perimeter (mm) | 3.75 ± 0.21 | 3.73 ± 0.26 | 0.8801 |
| Length (mm) | 15.01 ± 0.28 | 14.80 ± 0.27 | 0.1624 |
| Marrow Area (mm^2) | 1.12 ± 0.13 | 1.11 ± 0.15 | 0.8990 |
| Maximum Distance from Centroid (mm) | 2.00 ± 0.10 | 2.01 ± 0.12 | 0.9566 |
| Maximum Moment of Inertia (mm^4) | 0.271 ± 0.053 | 0.261 ± 0.063 | 0.7575 |
| Minimum Distance from Centroid (mm) | 1.322 ± 0.087 | 1.26 ± 0.11 | 0.3109 |
| Minimum Moment of Inertia (mm^4) | 0.141 ± 0.033 | 0.128 ± 0.040 | 0.5182 |
| Periosteal Perimeter (mm) | 4.97 ± 0.34 | 4.78 ± 0.38 | 0.3487 |
| Polar Moment of Inertia (mm^4) | 0.412 ± 0.086 | 0.39 ± 0.10 | 0.6589 |
| Pore Area (mm^2) | 0.0027 ± 0.0009 | 0.0020 ± 0.0004 | 0.0725 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.269 ± 0.038 | 0.258 ± 0.047 | 0.6271 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.211 ± 0.033 | 0.198 ± 0.044 | 0.5539 |
| Tissue Mineral Density (mg/ccm HA) | 1,219.11 ± 8.48 | 1,217.06 ± 4.89 | 0.5895 |
| Total Area (mm^2) | 1.92 ± 0.20 | 1.87 ± 0.25 | 0.6727 |