Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Npm3 KO Male
M
12wk
B6N(Cg)-Npm3<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Npm3 KO Female
F
12wk
B6N(Cg)-Npm3<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Npm3 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Npm3 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Npm3 WT Male (Mean ± SD) | Npm3 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.07 ± 1.17 | 25.86 ± 1.17 | 0.7485 |
| Bone Mineral Density (mg/ccm HA) | 1,160.31 ± 10.68 | 1,149.47 ± 3.58 | 0.0325* |
| Cortical Area (mm^2) | 0.723 ± 0.048 | 0.767 ± 0.044 | 0.0968 |
| Cortical Area / Total Area (%) | 42.04 ± 2.28 | 41.69 ± 1.61 | 0.7442 |
| Cortical Mask (dimensionless) | 0.725 ± 0.048 | 0.769 ± 0.044 | 0.0959 |
| Cortical Porosity (%) | 0.268 ± 0.023 | 0.276 ± 0.031 | 0.6035 |
| Cortical Thickness (mm) | 0.165 ± 0.011 | 0.1702 ± 0.0047 | 0.2655 |
| Endocortical Perimeter (mm) | 3.534 ± 0.078 | 3.67 ± 0.22 | 0.1335 |
| Length (mm) | 14.76 ± 0.12 | 14.87 ± 0.22 | 0.2841 |
| Marrow Area (mm^2) | 0.994 ± 0.044 | 1.08 ± 0.13 | 0.1312 |
| Maximum Distance from Centroid (mm) | 1.909 ± 0.058 | 1.99 ± 0.11 | 0.1040 |
| Maximum Moment of Inertia (mm^4) | 0.223 ± 0.017 | 0.263 ± 0.044 | 0.0403* |
| Minimum Distance from Centroid (mm) | 1.221 ± 0.027 | 1.259 ± 0.067 | 0.1799 |
| Minimum Moment of Inertia (mm^4) | 0.1109 ± 0.0093 | 0.124 ± 0.020 | 0.1444 |
| Periosteal Perimeter (mm) | 4.549 ± 0.090 | 4.80 ± 0.33 | 0.0930 |
| Polar Moment of Inertia (mm^4) | 0.334 ± 0.025 | 0.387 ± 0.062 | 0.0569 |
| Pore Area (mm^2) | 0.0019 ± 0.0002 | 0.0021 ± 0.0002 | 0.1216 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.234 ± 0.013 | 0.263 ± 0.029 | 0.0294* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.182 ± 0.012 | 0.196 ± 0.021 | 0.1440 |
| Tissue Mineral Density (mg/ccm HA) | 1,225.85 ± 8.99 | 1,210.82 ± 4.69 | 0.0015* |
| Total Area (mm^2) | 1.719 ± 0.050 | 1.85 ± 0.17 | 0.0800 |