Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Ipp KO Male
M
12wk
B6N(Cg)-Ipp<tm1.1(KOMP)-Vlcg>/J (C57BL/6NTac)
• KO/KO
Ipp KO Female
F
12wk
B6N(Cg)-Ipp<tm1.1(KOMP)-Vlcg>/J (C57BL/6NTac)
• KO/KO
Ipp WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Ipp WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Ipp WT Male (Mean ± SD) | Ipp KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.47 ± 1.55 | 24.11 ± 0.81 | 0.6072 |
| Bone Mineral Density (mg/ccm HA) | 1,131.94 ± 7.26 | 1,142.19 ± 5.62 | 0.0104* |
| Cortical Area (mm^2) | 0.648 ± 0.027 | 0.712 ± 0.050 | 0.0109* |
| Cortical Area / Total Area (%) | 38.74 ± 1.20 | 39.31 ± 1.00 | 0.3524 |
| Cortical Mask (dimensionless) | 0.650 ± 0.028 | 0.714 ± 0.050 | 0.0106* |
| Cortical Porosity (%) | 0.260 ± 0.017 | 0.317 ± 0.044 | 0.0063* |
| Cortical Thickness (mm) | 0.1493 ± 0.0050 | 0.1601 ± 0.0096 | 0.0235* |
| Endocortical Perimeter (mm) | 3.586 ± 0.088 | 3.71 ± 0.13 | 0.0580 |
| Length (mm) | 14.56 ± 0.15 | 14.87 ± 0.21 | 0.0084* |
| Marrow Area (mm^2) | 1.024 ± 0.050 | 1.097 ± 0.078 | 0.0574 |
| Maximum Distance from Centroid (mm) | 1.858 ± 0.051 | 1.929 ± 0.086 | 0.0811 |
| Maximum Moment of Inertia (mm^4) | 0.196 ± 0.016 | 0.236 ± 0.033 | 0.0127* |
| Minimum Distance from Centroid (mm) | 1.221 ± 0.037 | 1.283 ± 0.039 | 0.0087* |
| Minimum Moment of Inertia (mm^4) | 0.1008 ± 0.0074 | 0.118 ± 0.015 | 0.0214* |
| Periosteal Perimeter (mm) | 4.44 ± 0.16 | 4.76 ± 0.24 | 0.0127* |
| Polar Moment of Inertia (mm^4) | 0.297 ± 0.022 | 0.353 ± 0.048 | 0.0141* |
| Pore Area (mm^2) | 0.0017 ± 0.0001 | 0.0023 ± 0.0004 | 0.0021* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.211 ± 0.012 | 0.244 ± 0.026 | 0.0083* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.1651 ± 0.0086 | 0.183 ± 0.019 | 0.0392* |
| Tissue Mineral Density (mg/ccm HA) | 1,198.58 ± 7.48 | 1,207.48 ± 5.74 | 0.0256* |
| Total Area (mm^2) | 1.674 ± 0.066 | 1.81 ± 0.12 | 0.0215* |