Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Adck5 KO Male
M
12wk
B6N(Cg)-Adck5<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Adck5 KO Female
F
12wk
B6N(Cg)-Adck5<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Adck5 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Adck5 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Adck5 WT Male (Mean ± SD) | Adck5 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 25.94 ± 1.77 | 24.54 ± 1.17 | 0.1027 |
| Bone Mineral Density (mg/ccm HA) | 1,137.51 ± 6.51 | 1,149.54 ± 11.21 | 0.0278* |
| Cortical Area (mm^2) | 0.786 ± 0.095 | 0.724 ± 0.090 | 0.2318 |
| Cortical Area / Total Area (%) | 39.43 ± 1.55 | 41.58 ± 2.02 | 0.0417* |
| Cortical Mask (dimensionless) | 0.788 ± 0.095 | 0.726 ± 0.090 | 0.2307 |
| Cortical Porosity (%) | 0.291 ± 0.030 | 0.265 ± 0.023 | 0.0833 |
| Cortical Thickness (mm) | 0.167 ± 0.013 | 0.166 ± 0.014 | 0.9285 |
| Endocortical Perimeter (mm) | 3.88 ± 0.25 | 3.57 ± 0.22 | 0.0242* |
| Length (mm) | 14.97 ± 0.28 | 14.91 ± 0.24 | 0.6900 |
| Marrow Area (mm^2) | 1.21 ± 0.15 | 1.02 ± 0.13 | 0.0231* |
| Maximum Distance from Centroid (mm) | 2.03 ± 0.11 | 1.90 ± 0.12 | 0.0585 |
| Maximum Moment of Inertia (mm^4) | 0.287 ± 0.062 | 0.231 ± 0.055 | 0.0964 |
| Minimum Distance from Centroid (mm) | 1.33 ± 0.10 | 1.227 ± 0.073 | 0.0434* |
| Minimum Moment of Inertia (mm^4) | 0.146 ± 0.033 | 0.114 ± 0.026 | 0.0698 |
| Periosteal Perimeter (mm) | 5.02 ± 0.41 | 4.66 ± 0.39 | 0.1161 |
| Polar Moment of Inertia (mm^4) | 0.432 ± 0.094 | 0.345 ± 0.081 | 0.0842 |
| Pore Area (mm^2) | 0.0023 ± 0.0005 | 0.0019 ± 0.0003 | 0.0860 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.280 ± 0.050 | 0.240 ± 0.042 | 0.1302 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.216 ± 0.036 | 0.184 ± 0.031 | 0.1010 |
| Tissue Mineral Density (mg/ccm HA) | 1,197.37 ± 7.25 | 1,213.44 ± 16.50 | 0.0409* |
| Total Area (mm^2) | 1.99 ± 0.24 | 1.74 ± 0.20 | 0.0519 |