Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Acap1 KO Male
M
12wk
B6N(Cg)-Acap1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Acap1 KO Female
F
12wk
B6N(Cg)-Acap1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Acap1 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Acap1 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Acap1 WT Male (Mean ± SD) | Acap1 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 25.94 ± 1.77 | 23.93 ± 1.23 | 0.0656 |
| Bone Mineral Density (mg/ccm HA) | 1,137.51 ± 6.51 | 1,149.36 ± 11.45 | 0.0514 |
| Cortical Area (mm^2) | 0.786 ± 0.095 | 0.730 ± 0.038 | 0.2691 |
| Cortical Area / Total Area (%) | 39.43 ± 1.55 | 39.82 ± 2.11 | 0.7302 |
| Cortical Mask (dimensionless) | 0.788 ± 0.095 | 0.732 ± 0.037 | 0.2733 |
| Cortical Porosity (%) | 0.291 ± 0.030 | 0.38 ± 0.22 | 0.3299 |
| Cortical Thickness (mm) | 0.167 ± 0.013 | 0.1618 ± 0.0095 | 0.5321 |
| Endocortical Perimeter (mm) | 3.88 ± 0.25 | 3.72 ± 0.16 | 0.2470 |
| Length (mm) | 14.97 ± 0.28 | 14.730 ± 0.085 | 0.0632 |
| Marrow Area (mm^2) | 1.21 ± 0.15 | 1.103 ± 0.093 | 0.2327 |
| Maximum Distance from Centroid (mm) | 2.03 ± 0.11 | 1.973 ± 0.072 | 0.3494 |
| Maximum Moment of Inertia (mm^4) | 0.287 ± 0.062 | 0.253 ± 0.025 | 0.3030 |
| Minimum Distance from Centroid (mm) | 1.33 ± 0.10 | 1.254 ± 0.035 | 0.1547 |
| Minimum Moment of Inertia (mm^4) | 0.146 ± 0.033 | 0.117 ± 0.012 | 0.1225 |
| Periosteal Perimeter (mm) | 5.02 ± 0.41 | 4.73 ± 0.14 | 0.1994 |
| Polar Moment of Inertia (mm^4) | 0.432 ± 0.094 | 0.370 ± 0.037 | 0.2197 |
| Pore Area (mm^2) | 0.0023 ± 0.0005 | 0.0027 ± 0.0015 | 0.5252 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.280 ± 0.050 | 0.256 ± 0.017 | 0.3498 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.216 ± 0.036 | 0.187 ± 0.015 | 0.1434 |
| Tissue Mineral Density (mg/ccm HA) | 1,197.37 ± 7.25 | 1,214.78 ± 8.75 | 0.0044* |
| Total Area (mm^2) | 1.99 ± 0.24 | 1.84 ± 0.11 | 0.2233 |