Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
A1cf KO Male
M
12wk
B6N(Cg)-A1cf<tmib(EUCOMM)Hmg>/J (C57BL/6NTac)
• KO/KO
A1cf KO Female
F
12wk
B6N(Cg)-A1cf<tmib(EUCOMM)Hmg>/J (C57BL/6NTac)
• KO/KO
A1cf WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
A1cf WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | A1cf WT Male (Mean ± SD) | A1cf KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 20.33 ± 0.89 | 22.99 ± 3.29 | 0.0980 |
| Bone Mineral Density (mg/ccm HA) | 1,162.20 ± 7.10 | 1,161.91 ± 9.46 | 0.9482 |
| Cortical Area (mm^2) | 0.641 ± 0.049 | 0.74 ± 0.13 | 0.0640 |
| Cortical Area / Total Area (%) | 38.69 ± 1.39 | 42.57 ± 1.02 | <0.001* |
| Cortical Mask (dimensionless) | 0.643 ± 0.049 | 0.75 ± 0.13 | 0.0638 |
| Cortical Porosity (%) | 0.210 ± 0.032 | 0.258 ± 0.074 | 0.1338 |
| Cortical Thickness (mm) | 0.1494 ± 0.0092 | 0.173 ± 0.013 | 0.0015* |
| Endocortical Perimeter (mm) | 3.569 ± 0.096 | 3.54 ± 0.33 | 0.8286 |
| Length (mm) | 14.42 ± 0.16 | 14.77 ± 0.63 | 0.1842 |
| Marrow Area (mm^2) | 1.014 ± 0.055 | 1.01 ± 0.19 | 0.9140 |
| Maximum Distance from Centroid (mm) | 1.870 ± 0.067 | 1.86 ± 0.21 | 0.9023 |
| Maximum Moment of Inertia (mm^4) | 0.194 ± 0.027 | 0.231 ± 0.088 | 0.3006 |
| Minimum Distance from Centroid (mm) | 1.226 ± 0.039 | 1.292 ± 0.095 | 0.1104 |
| Minimum Moment of Inertia (mm^4) | 0.099 ± 0.012 | 0.125 ± 0.042 | 0.1378 |
| Periosteal Perimeter (mm) | 4.36 ± 0.15 | 4.56 ± 0.75 | 0.5139 |
| Polar Moment of Inertia (mm^4) | 0.292 ± 0.038 | 0.36 ± 0.13 | 0.2355 |
| Pore Area (mm^2) | 0.0014 ± 0.0003 | 0.0020 ± 0.0008 | 0.0835 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.206 ± 0.021 | 0.241 ± 0.064 | 0.1935 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.161 ± 0.015 | 0.190 ± 0.050 | 0.1614 |
| Tissue Mineral Density (mg/ccm HA) | 1,237.11 ± 7.41 | 1,226.27 ± 7.69 | 0.0177* |
| Total Area (mm^2) | 1.657 ± 0.095 | 1.75 ± 0.32 | 0.4713 |