Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Hyal3 KO Male
M
12wk
B6N(Cg)-Hyal3<tm1.1(KOMP)-Vlcg>/J (C57BL/6NTac)
• KO/KO
Hyal3 KO Female
F
12wk
B6N(Cg)-Hyal3<tm1.1(KOMP)-Vlcg>/J (C57BL/6NTac)
• KO/KO
Hyal3 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Hyal3 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Hyal3 WT Male (Mean ± SD) | Hyal3 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.54 ± 1.19 | 24.29 ± 2.53 | 0.8254 |
| Bone Mineral Density (mg/ccm HA) | 1,130.64 ± 7.19 | 1,149.53 ± 9.48 | <0.001* |
| Cortical Area (mm^2) | 0.634 ± 0.033 | 0.729 ± 0.045 | <0.001* |
| Cortical Area / Total Area (%) | 38.47 ± 1.20 | 40.64 ± 1.52 | 0.0101* |
| Cortical Mask (dimensionless) | 0.636 ± 0.033 | 0.731 ± 0.045 | <0.001* |
| Cortical Porosity (%) | 0.271 ± 0.032 | 0.292 ± 0.059 | 0.4301 |
| Cortical Thickness (mm) | 0.1471 ± 0.0054 | 0.1632 ± 0.0051 | <0.001* |
| Endocortical Perimeter (mm) | 3.566 ± 0.072 | 3.66 ± 0.18 | 0.2660 |
| Length (mm) | 12.71 ± 4.81 | 14.89 ± 0.25 | 0.2506 |
| Marrow Area (mm^2) | 1.013 ± 0.041 | 1.07 ± 0.11 | 0.2561 |
| Maximum Distance from Centroid (mm) | 1.848 ± 0.048 | 1.94 ± 0.11 | 0.0663 |
| Maximum Moment of Inertia (mm^4) | 0.190 ± 0.016 | 0.241 ± 0.035 | 0.0034* |
| Minimum Distance from Centroid (mm) | 1.209 ± 0.026 | 1.247 ± 0.069 | 0.1945 |
| Minimum Moment of Inertia (mm^4) | 0.0968 ± 0.0086 | 0.117 ± 0.019 | 0.0220* |
| Periosteal Perimeter (mm) | 4.40 ± 0.13 | 4.71 ± 0.33 | 0.0338* |
| Polar Moment of Inertia (mm^4) | 0.287 ± 0.023 | 0.358 ± 0.053 | 0.0059* |
| Pore Area (mm^2) | 0.0017 ± 0.0002 | 0.0021 ± 0.0004 | 0.0440* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.205 ± 0.013 | 0.248 ± 0.022 | <0.001* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.160 ± 0.012 | 0.187 ± 0.019 | 0.0069* |
| Tissue Mineral Density (mg/ccm HA) | 1,198.63 ± 8.01 | 1,213.33 ± 10.63 | 0.0111* |
| Total Area (mm^2) | 1.648 ± 0.062 | 1.80 ± 0.15 | 0.0289* |