Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Akr1d1 KO Male
M
12wk
B6N(Cg)-Akr1d1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Akr1d1 KO Female
F
12wk
B6N(Cg)-Akr1d1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Akr1d1 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Akr1d1 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Akr1d1 WT Male (Mean ± SD) | Akr1d1 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.07 ± 1.17 | 24.91 ± 1.62 | 0.1467 |
| Bone Mineral Density (mg/ccm HA) | 1,160.31 ± 10.68 | 1,147.58 ± 9.10 | 0.0308* |
| Cortical Area (mm^2) | 0.723 ± 0.048 | 0.727 ± 0.036 | 0.8765 |
| Cortical Area / Total Area (%) | 42.04 ± 2.28 | 42.77 ± 1.47 | 0.4869 |
| Cortical Mask (dimensionless) | 0.725 ± 0.048 | 0.729 ± 0.037 | 0.8492 |
| Cortical Porosity (%) | 0.268 ± 0.023 | 0.38 ± 0.15 | 0.0737 |
| Cortical Thickness (mm) | 0.165 ± 0.011 | 0.1702 ± 0.0072 | 0.2950 |
| Endocortical Perimeter (mm) | 3.534 ± 0.078 | 3.49 ± 0.11 | 0.4046 |
| Length (mm) | 14.76 ± 0.12 | 14.83 ± 0.28 | 0.5822 |
| Marrow Area (mm^2) | 0.994 ± 0.044 | 0.970 ± 0.061 | 0.4117 |
| Maximum Distance from Centroid (mm) | 1.909 ± 0.058 | 1.902 ± 0.055 | 0.8204 |
| Maximum Moment of Inertia (mm^4) | 0.223 ± 0.017 | 0.225 ± 0.023 | 0.9127 |
| Minimum Distance from Centroid (mm) | 1.221 ± 0.027 | 1.218 ± 0.038 | 0.8897 |
| Minimum Moment of Inertia (mm^4) | 0.1109 ± 0.0093 | 0.108 ± 0.011 | 0.6314 |
| Periosteal Perimeter (mm) | 4.549 ± 0.090 | 4.54 ± 0.26 | 0.9221 |
| Polar Moment of Inertia (mm^4) | 0.334 ± 0.025 | 0.333 ± 0.032 | 0.9261 |
| Pore Area (mm^2) | 0.0019 ± 0.0002 | 0.0028 ± 0.0012 | 0.0878 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.234 ± 0.013 | 0.236 ± 0.018 | 0.8139 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.182 ± 0.012 | 0.177 ± 0.013 | 0.5456 |
| Tissue Mineral Density (mg/ccm HA) | 1,225.85 ± 8.99 | 1,211.39 ± 9.33 | 0.0105* |
| Total Area (mm^2) | 1.719 ± 0.050 | 1.700 ± 0.084 | 0.6060 |