Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Epb41l4a KO Male
M
12wk
B6N(Cg)-Epb41la tm1b(KOMP)Mbp/2J (C57BL/6NTac)
• KO/KO
Epb41l4a KO Female
F
12wk
B6N(Cg)-Epb41la tm1b(KOMP)Mbp/2J (C57BL/6NTac)
• KO/KO
Epb41l4a WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Epb41l4a WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Epb41l4a WT Male (Mean ± SD) | Epb41l4a KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 26.15 ± 1.38 | 26.02 ± 2.59 | 0.9151 |
| Bone Mineral Density (mg/ccm HA) | 1,120.22 ± 8.07 | 1,160.24 ± 13.59 | <0.001* |
| Cortical Area (mm^2) | 0.740 ± 0.018 | 0.665 ± 0.076 | 0.0534 |
| Cortical Area / Total Area (%) | 41.46 ± 1.40 | 39.57 ± 1.20 | 0.0223* |
| Cortical Mask (dimensionless) | 0.743 ± 0.018 | 0.667 ± 0.077 | 0.0518 |
| Cortical Porosity (%) | 0.372 ± 0.077 | 0.243 ± 0.052 | 0.0039* |
| Cortical Thickness (mm) | 0.1664 ± 0.0062 | 0.154 ± 0.012 | 0.0312* |
| Endocortical Perimeter (mm) | 3.620 ± 0.094 | 3.56 ± 0.15 | 0.4182 |
| Length (mm) | 14.65 ± 0.12 | 14.45 ± 0.32 | 0.1580 |
| Marrow Area (mm^2) | 1.044 ± 0.054 | 1.012 ± 0.085 | 0.4304 |
| Maximum Distance from Centroid (mm) | 1.972 ± 0.042 | 1.88 ± 0.11 | 0.0950 |
| Maximum Moment of Inertia (mm^4) | 0.245 ± 0.010 | 0.206 ± 0.046 | 0.0830 |
| Minimum Distance from Centroid (mm) | 1.241 ± 0.030 | 1.231 ± 0.046 | 0.6548 |
| Minimum Moment of Inertia (mm^4) | 0.1146 ± 0.0072 | 0.104 ± 0.017 | 0.1434 |
| Periosteal Perimeter (mm) | 4.791 ± 0.079 | 4.44 ± 0.34 | 0.0428* |
| Polar Moment of Inertia (mm^4) | 0.360 ± 0.015 | 0.309 ± 0.063 | 0.0998 |
| Pore Area (mm^2) | 0.0028 ± 0.0006 | 0.0016 ± 0.0005 | 0.0024* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.2487 ± 0.0086 | 0.217 ± 0.037 | 0.0792 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.1847 ± 0.0075 | 0.167 ± 0.022 | 0.1107 |
| Tissue Mineral Density (mg/ccm HA) | 1,187.33 ± 8.88 | 1,225.47 ± 16.44 | <0.001* |
| Total Area (mm^2) | 1.787 ± 0.056 | 1.68 ± 0.16 | 0.1162 |