Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Nes KO Male
M
12wk
B6N(Cg)-Nes<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Nes KO Female
F
12wk
B6N(Cg)-Nes<tm1b(KOMP)Wtsi>/J (C57BL/6NTac)
• KO/KO
Nes WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Nes WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Nes WT Male (Mean ± SD) | Nes KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 22.75 ± 1.50 | 24.12 ± 1.86 | 0.1504 |
| Bone Mineral Density (mg/ccm HA) | 1,171.19 ± 19.11 | 1,176.00 ± 5.46 | 0.5321 |
| Cortical Area (mm^2) | 0.644 ± 0.070 | 0.682 ± 0.032 | 0.2197 |
| Cortical Area / Total Area (%) | 40.67 ± 2.69 | 40.26 ± 0.67 | 0.7073 |
| Cortical Mask (dimensionless) | 0.646 ± 0.070 | 0.684 ± 0.032 | 0.2177 |
| Cortical Porosity (%) | 0.240 ± 0.044 | 0.278 ± 0.053 | 0.1655 |
| Cortical Thickness (mm) | 0.155 ± 0.015 | 0.1576 ± 0.0049 | 0.6598 |
| Endocortical Perimeter (mm) | 3.43 ± 0.10 | 3.561 ± 0.059 | 0.0112* |
| Length (mm) | 14.46 ± 0.35 | 14.68 ± 0.15 | 0.1544 |
| Marrow Area (mm^2) | 0.936 ± 0.057 | 1.009 ± 0.033 | 0.0107* |
| Maximum Distance from Centroid (mm) | 1.782 ± 0.049 | 1.889 ± 0.063 | 0.0033* |
| Maximum Moment of Inertia (mm^4) | 0.178 ± 0.028 | 0.215 ± 0.023 | 0.0180* |
| Minimum Distance from Centroid (mm) | 1.224 ± 0.045 | 1.219 ± 0.022 | 0.8082 |
| Minimum Moment of Inertia (mm^4) | 0.096 ± 0.014 | 0.1031 ± 0.0066 | 0.2571 |
| Periosteal Perimeter (mm) | 4.21 ± 0.23 | 4.49 ± 0.18 | 0.0221* |
| Polar Moment of Inertia (mm^4) | 0.274 ± 0.041 | 0.318 ± 0.029 | 0.0374* |
| Pore Area (mm^2) | 0.0016 ± 0.0004 | 0.0019 ± 0.0004 | 0.1329 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.199 ± 0.027 | 0.227 ± 0.018 | 0.0404* |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.157 ± 0.019 | 0.1690 ± 0.0095 | 0.1420 |
| Tissue Mineral Density (mg/ccm HA) | 1,245.49 ± 17.48 | 1,250.63 ± 6.38 | 0.4769 |
| Total Area (mm^2) | 1.582 ± 0.100 | 1.693 ± 0.062 | 0.0259* |