Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Chek2 KO Male
M
12wk
B6N(Cg)-Chek2<tm1b(EUCOMM)Hmg>/J (C57BL/6NTac)
• KO/KO
Chek2 KO Female
F
12wk
B6N(Cg)-Chek2<tm1b(EUCOMM)Hmg>/J (C57BL/6NTac)
• KO/KO
Chek2 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Chek2 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Chek2 WT Male (Mean ± SD) | Chek2 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.87 ± 2.15 | 21.16 ± 2.02 | 0.0050* |
| Bone Mineral Density (mg/ccm HA) | 1,150.63 ± 12.21 | 1,156.62 ± 5.91 | 0.2627 |
| Cortical Area (mm^2) | 0.760 ± 0.090 | 0.689 ± 0.072 | 0.1272 |
| Cortical Area / Total Area (%) | 40.37 ± 1.94 | 40.62 ± 1.07 | 0.7696 |
| Cortical Mask (dimensionless) | 0.762 ± 0.091 | 0.691 ± 0.072 | 0.1278 |
| Cortical Porosity (%) | 0.284 ± 0.040 | 0.284 ± 0.056 | 0.9887 |
| Cortical Thickness (mm) | 0.168 ± 0.011 | 0.1606 ± 0.0097 | 0.2420 |
| Endocortical Perimeter (mm) | 3.75 ± 0.31 | 3.55 ± 0.20 | 0.1674 |
| Length (mm) | 14.91 ± 0.33 | 14.61 ± 0.37 | 0.1400 |
| Marrow Area (mm^2) | 1.13 ± 0.19 | 1.01 ± 0.11 | 0.1614 |
| Maximum Distance from Centroid (mm) | 1.96 ± 0.17 | 1.86 ± 0.12 | 0.2655 |
| Maximum Moment of Inertia (mm^4) | 0.258 ± 0.070 | 0.214 ± 0.051 | 0.2070 |
| Minimum Distance from Centroid (mm) | 1.32 ± 0.10 | 1.240 ± 0.051 | 0.0956 |
| Minimum Moment of Inertia (mm^4) | 0.137 ± 0.037 | 0.107 ± 0.019 | 0.0797 |
| Periosteal Perimeter (mm) | 4.90 ± 0.54 | 4.47 ± 0.43 | 0.1293 |
| Polar Moment of Inertia (mm^4) | 0.39 ± 0.11 | 0.321 ± 0.069 | 0.1501 |
| Pore Area (mm^2) | 0.0022 ± 0.0004 | 0.0020 ± 0.0005 | 0.4740 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.259 ± 0.048 | 0.227 ± 0.040 | 0.1977 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.204 ± 0.040 | 0.171 ± 0.024 | 0.0801 |
| Tissue Mineral Density (mg/ccm HA) | 1,214.53 ± 10.99 | 1,225.11 ± 6.30 | 0.0443* |
| Total Area (mm^2) | 1.89 ± 0.27 | 1.70 ± 0.18 | 0.1405 |