Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Il6st KO Male
M
12wk
B6N(Cg)-Il6st<tm1b(KOMP)Mbp>/J (C57BL/6NTac)
• KO/KO
Il6st KO Female
F
12wk
B6N(Cg)-Il6st<tm1b(KOMP)Mbp>/J (C57BL/6NTac)
• KO/KO
Il6st WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Il6st WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Il6st WT Male (Mean ± SD) | Il6st KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 22.00 ± 3.26 | 24.26 ± 2.04 | 0.1420 |
| Bone Mineral Density (mg/ccm HA) | 1,179.19 ± 5.92 | 1,148.36 ± 16.08 | <0.001* |
| Cortical Area (mm^2) | 0.728 ± 0.082 | 0.71 ± 0.10 | 0.7656 |
| Cortical Area / Total Area (%) | 41.23 ± 1.09 | 37.36 ± 2.60 | 0.0027* |
| Cortical Mask (dimensionless) | 0.730 ± 0.082 | 0.72 ± 0.10 | 0.7700 |
| Cortical Porosity (%) | 0.279 ± 0.043 | 0.313 ± 0.056 | 0.2284 |
| Cortical Thickness (mm) | 0.165 ± 0.010 | 0.154 ± 0.019 | 0.1729 |
| Endocortical Perimeter (mm) | 3.60 ± 0.21 | 3.86 ± 0.13 | 0.0182* |
| Length (mm) | 14.67 ± 0.36 | 14.65 ± 0.35 | 0.9132 |
| Marrow Area (mm^2) | 1.04 ± 0.13 | 1.187 ± 0.082 | 0.0193* |
| Maximum Distance from Centroid (mm) | 1.88 ± 0.15 | 2.01 ± 0.11 | 0.0913 |
| Maximum Moment of Inertia (mm^4) | 0.227 ± 0.059 | 0.257 ± 0.055 | 0.3485 |
| Minimum Distance from Centroid (mm) | 1.274 ± 0.062 | 1.302 ± 0.053 | 0.3683 |
| Minimum Moment of Inertia (mm^4) | 0.121 ± 0.026 | 0.125 ± 0.027 | 0.8207 |
| Periosteal Perimeter (mm) | 4.60 ± 0.43 | 4.88 ± 0.44 | 0.2503 |
| Polar Moment of Inertia (mm^4) | 0.349 ± 0.084 | 0.381 ± 0.081 | 0.4711 |
| Pore Area (mm^2) | 0.0021 ± 0.0005 | 0.0023 ± 0.0007 | 0.5199 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.238 ± 0.042 | 0.253 ± 0.044 | 0.5171 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.189 ± 0.031 | 0.190 ± 0.034 | 0.9530 |
| Tissue Mineral Density (mg/ccm HA) | 1,249.02 ± 9.28 | 1,218.14 ± 14.21 | <0.001* |
| Total Area (mm^2) | 1.77 ± 0.20 | 1.90 ± 0.16 | 0.1943 |