Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Col18a1 KO Male
M
12wk
B6N(Cg)-Col18a1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Col18a1 KO Female
F
12wk
B6N(Cg)-Col18a1<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Col18a1 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Col18a1 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Col18a1 WT Male (Mean ± SD) | Col18a1 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 23.73 ± 2.28 | 23.07 ± 1.28 | 0.5155 |
| Bone Mineral Density (mg/ccm HA) | 1,154.70 ± 21.42 | 1,163.13 ± 10.50 | 0.3652 |
| Cortical Area (mm^2) | 0.696 ± 0.085 | 0.679 ± 0.072 | 0.6836 |
| Cortical Area / Total Area (%) | 39.54 ± 2.65 | 40.17 ± 1.70 | 0.6080 |
| Cortical Mask (dimensionless) | 0.698 ± 0.085 | 0.680 ± 0.073 | 0.6794 |
| Cortical Porosity (%) | 0.276 ± 0.021 | 0.0024 ± 0.0003 | <0.001* |
| Cortical Thickness (mm) | 0.159 ± 0.015 | 0.156 ± 0.010 | 0.6915 |
| Endocortical Perimeter (mm) | 3.65 ± 0.25 | 3.56 ± 0.23 | 0.4922 |
| Length (mm) | 14.29 ± 0.66 | 14.54 ± 0.32 | 0.3949 |
| Marrow Area (mm^2) | 1.07 ± 0.15 | 1.01 ± 0.14 | 0.4990 |
| Maximum Distance from Centroid (mm) | 1.91 ± 0.14 | 1.86 ± 0.12 | 0.4470 |
| Maximum Moment of Inertia (mm^4) | 0.225 ± 0.055 | 0.206 ± 0.048 | 0.4972 |
| Minimum Distance from Centroid (mm) | 1.284 ± 0.051 | 1.247 ± 0.076 | 0.3059 |
| Minimum Moment of Inertia (mm^4) | 0.114 ± 0.026 | 0.109 ± 0.026 | 0.6928 |
| Periosteal Perimeter (mm) | 4.47 ± 0.52 | 4.42 ± 0.35 | 0.8545 |
| Polar Moment of Inertia (mm^4) | 0.339 ± 0.081 | 0.315 ± 0.073 | 0.5560 |
| Pore Area (mm^2) | 0.0019 ± 0.0003 | 0.0016 ± 0.0003 | 0.0781 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.233 ± 0.041 | 0.219 ± 0.036 | 0.5242 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.177 ± 0.034 | 0.173 ± 0.030 | 0.8105 |
| Tissue Mineral Density (mg/ccm HA) | 1,221.28 ± 25.22 | 1,234.32 ± 10.34 | 0.2364 |
| Total Area (mm^2) | 1.76 ± 0.21 | 1.69 ± 0.20 | 0.5356 |